Featured Research

from universities, journals, and other organizations

Early and Easy Detection Of Alzheimer's Disease?

Date:
June 17, 2009
Source:
McGill University
Summary:
A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered. There is currently no accepted blood test for Alzheimer's, and the diagnosis is usually based on expensive and labor-intensive neurological, neuropsychological and neuroimaging evaluations.

A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital (JGH).

Related Articles


There is currently no accepted blood test for Alzheimer's, and the diagnosis is usually based on expensive and labour-intensive neurological, neuropsychological and neuroimaging evaluations.

Dr. Hyman Schipper and colleagues at the Lady Davis Institute and McGill University utilized a new minimally-invasive technique called near-infrared (NIR) biospectroscopy to identify changes in the blood plasma of Alzheimer's patients, changes which can be detected very early after onset, and possibly in pre-clinical stages of the disease.

Biospectroscopy is the medical form of spectroscopy, the science of detecting the composition of substances using light or other forms of energy. In NIR spectroscopy, different substances emit or reflect light at specific, detectable wavelengths.

In this study, Schipper and his colleague Dr. David Burns – head of McGill's Biomedical Laboratory for Informatics, Imaging and Spectroscopy at the department of chemistry – applied near-infrared light to blood plasma samples taken from patients with early Alzheimer's dementia, mild cognitive impairment (MCI) == an intermediate state between normal cognition and dementia -- and healthy elderly control subjects at the JGH/McGill Memory Clinic. Using this technique, the researchers were able to distinguish Alzheimer's from healthy controls with 80 per cent sensitivity (correct identification of patients with the disease) and 77 per cent specificity (correct identification of persons without the disease). A significant number of subjects with MCI tested positively with the Alzheimer group, indicating that the test may be capable of detecting Alzheimer disease even before patients' symptoms meet clinical criteria for dementia.

"We are very encouraged by these data and look forward to testing this potential diagnostic tool in larger-scale studies", said Schipper, Director of the Centre for Neurotranslational Research at the JGH and professor of neurology and medicine at McGill. Researchers have been searching for a minimally-invasive biological marker that differentiates Alzheimer's disease from normal aging and other neurodegenerative conditions for decades.

"The advent of a simple blood test for the diagnosis of early Alzheimer's", remarked Schipper, "would represent a major achievement in the management of this common disorder".


Story Source:

The above story is based on materials provided by McGill University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Near-Infrared Spectroscopy of Blood Plasma for Diagnosis of Sporadic Alzheimer Disease. Journal of Alzheimer's Disease, 17:2; June 8, 2009

Cite This Page:

McGill University. "Early and Easy Detection Of Alzheimer's Disease?." ScienceDaily. ScienceDaily, 17 June 2009. <www.sciencedaily.com/releases/2009/06/090616122113.htm>.
McGill University. (2009, June 17). Early and Easy Detection Of Alzheimer's Disease?. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2009/06/090616122113.htm
McGill University. "Early and Easy Detection Of Alzheimer's Disease?." ScienceDaily. www.sciencedaily.com/releases/2009/06/090616122113.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Foods to Battle Stress

The Best Foods to Battle Stress

Buzz60 (Feb. 26, 2015) If you&apos;re dealing with anxiety, there are a few foods that can help. Krystin Goodwin (@krystingoodwin) has the best foods to tame stress. Video provided by Buzz60
Powered by NewsLook.com
Sleeping Too Much Or Too Little Might Increase Stroke Risk

Sleeping Too Much Or Too Little Might Increase Stroke Risk

Newsy (Feb. 26, 2015) People who sleep more than eight hours per night are 45 percent more likely to have a stroke, according to a University of Cambridge study. Video provided by Newsy
Powered by NewsLook.com
Mayor Says District of Columbia to Go Ahead With Pot Legalization

Mayor Says District of Columbia to Go Ahead With Pot Legalization

Reuters - News Video Online (Feb. 25, 2015) Washington&apos;s mayor says the District of Columbia will move forward with marijuana legalization, despite pushback from Congress. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Marijuana Nowhere Near As Deadly As Alcohol: Study

Marijuana Nowhere Near As Deadly As Alcohol: Study

Newsy (Feb. 25, 2015) A new study says marijuana is about 114 times less deadly than alcohol. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins