Featured Research

from universities, journals, and other organizations

Buyer Beware: Estrogen Supplements Not As Effective As Claimed, Researchers Find

Date:
September 3, 2009
Source:
Purdue University
Summary:
Dietary supplements claiming to help postmenopausal women with bone health may not be doing what they say, according to new research.

Dietary supplements claiming to help postmenopausal women with bone health may not be doing what they say, according to new research from Purdue University.

Related Articles


"We found that some plant-derived isoflavones have a modest effect on suppressing bone loss during post-menopause, but more concerning is many dietary supplements that claim to have the power of estrogen do not," said Connie Weaver, distinguished professor of foods and nutrition. "It's buyer beware. Some of the supplements in our study claimed to be substitutes for estrogen, yet they weren't effective at all or weren't as effective as some of the current treatments for osteoporosis."

Women who are menopausal or postmenopausal produce less estrogen, and that leads to bone loss. More than 2 million women in the United States reach menopause each year, according to the National Women's Health Resource Center.

Estrogen hormone replacement therapy was the traditional treatment, but it is no longer recommended for the long term because of links to stroke, embolism and breast cancer. Some individuals have harmful side effects with long-term use of bisphosphonates, the current main class of osteoporosis treatment drugs.

"This is a reminder that it's better to build up a good healthy skeleton than to rely on a drug to fix it later," Weaver said. "Healthy bones can be maintained by a good diet that is rich in calcium and regular exercise that includes strength training."

Weaver, who also is co-director of the Botanicals Research Center for Age Related Diseases, and her team looked at four popular isoflavones: soy cotyledon, soy germ, red clover and kudzu. These plant-derived phytoestrogens are claimed to protect bone health from estrogen loss, which can lead to osteoporosis and even fractures.

The researchers compared the four isoflavones to a traditional bisphosphonate treatment, risedronate and estrogen plus progesterone. These traditional therapies decreased bone loss 22 percent to 24 percent, but only soy isoflavones from the cotyledon and germ significantly decreased bone loss by 9 percent and 5 percent, respectively. The findings are available online and will be published in the October edition of the Journal of Clinical Endocrinology and Metabolism.

The findings also indicate that the soy cotyledon was more effective because of its higher genistein content. Weaver's team is currently evaluating the role of genistein more closely.

"Before, we might have assumed that any isoflavone was equally effective, but we found that for a supplement to work it was because of the genistein content specifically," she said.

This work was funded by the National Institutes of Health and supplements were supplied by the dietary and health companies Cognis, Frutarom and Novagen. Weaver also is on the advisory board of Pharmative and Wyeth Global Nutrition. The Botanicals Research Center for Age Related Diseases is a partnership between Purdue and the University of Alabama-Birmingham.


Story Source:

The above story is based on materials provided by Purdue University. The original article was written by Amy Patterson Neubert. Note: Materials may be edited for content and length.


Cite This Page:

Purdue University. "Buyer Beware: Estrogen Supplements Not As Effective As Claimed, Researchers Find." ScienceDaily. ScienceDaily, 3 September 2009. <www.sciencedaily.com/releases/2009/09/090902151117.htm>.
Purdue University. (2009, September 3). Buyer Beware: Estrogen Supplements Not As Effective As Claimed, Researchers Find. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2009/09/090902151117.htm
Purdue University. "Buyer Beware: Estrogen Supplements Not As Effective As Claimed, Researchers Find." ScienceDaily. www.sciencedaily.com/releases/2009/09/090902151117.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins