Featured Research

from universities, journals, and other organizations

Kidney Transplants Generally Safe For Lupus Patients, New Study Suggests

Date:
October 31, 2009
Source:
American Society of Nephrology
Summary:
Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a new article. The findings indicate that having lupus should not keep individuals from seeking a kidney transplant if they need one. Contrary to previous studies, a new study suggests lupus patients who receive kidney transplants rarely develop lupus nephritis.

Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. The findings indicate that having lupus should not keep individuals from seeking a kidney transplant if they need one.

Related Articles


Individuals with the autoimmune disease systemic lupus erythematosus (lupus) can experience a number of medical complications, such as lupus nephritis, an inflammatory kidney disorder. Previous studies provide conflicting results about the incidence and severity of lupus nephritis in patients with a history of lupus who have undergone a kidney transplant. Some studies conclude that lupus nephritis is of little consequence while others report that the condition can increase the risk of kidney failure and the risk of death in recipients of a kidney transplant.

Gabriel Contreras, MD, MPH (University of Miami), and his colleagues conducted a thorough evaluation of the frequency of lupus nephritis in kidney transplant recipients and determined the risk this condition has for patients. They mined data from the United Network for Organ Sharing and studied 6850 patients with a history of lupus who received kidney transplants between 1987 and 2006.

The researchers found that lupus nephritis rarely developed in the transplanted kidneys of these lupus patients; it occurred in 2.44% of individuals in the study. When it did occur, lupus nephritis led to a 4-fold increased relative risk of kidney transplant failure; however, the overall risk for the loss of the new organ attributed to lupus developing in the transplanted kidneys was only 7%. During the study period of 19 years, 12.7% of patients died with only 0.4% patients dying in the group with lupus developing in the transplanted kidneys. The investigators also found that African Americans and young women were at higher risk for developing lupus nephritis in their transplanted kidney. Receiving a kidney transplant before or after starting dialysis did not affect one's risk. The type of kidney transplant (deceased vs living donor) also had no effect on a recipient's risk of developing lupus nephritis.

Study co-authors include Baudouin LeClercq (private practice) and Adela. Mattiazzi, Giselle Guerra, Hua Li, Leonardo Tamariz, Cristiane Carvalho, Warren Kupin, Isabel Jaraba, Decio Carvalho, Marco Ladino, and David Roth (University of Miami).


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Cite This Page:

American Society of Nephrology. "Kidney Transplants Generally Safe For Lupus Patients, New Study Suggests." ScienceDaily. ScienceDaily, 31 October 2009. <www.sciencedaily.com/releases/2009/10/091031152430.htm>.
American Society of Nephrology. (2009, October 31). Kidney Transplants Generally Safe For Lupus Patients, New Study Suggests. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2009/10/091031152430.htm
American Society of Nephrology. "Kidney Transplants Generally Safe For Lupus Patients, New Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2009/10/091031152430.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins