Featured Research

from universities, journals, and other organizations

New way to biopsy brain tumors in real time

Date:
November 14, 2009
Source:
St. Joseph's Hospital and Medical Center
Summary:
A new miniature, hand-held microscope may allow more precise removal of brain tumors and an easier recognition of tumor locations during surgery.

A new miniature, hand-held microscope may allow more precise removal of brain tumors and an easier recognition of tumor locations during surgery.

Neurosurgeons at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center are using the new miniature laser confocal microscope to view brain tumor regions during surgery and obtain digital images of the tumor and brain tissue. This was not previously possible without taking biopsies of the tissue.

The microscope is used to image the tissue after a fluorescent drug is injected into the patient and travels into the tumor. The first application of the technology in the research lab at Barrow showed that it was possible to distinguish cancer cells and the margin of the brain tumor without taking a biopsy. Barrow researchers also discovered that it was possible to obtain a digital video of the brain tumor to show blood flowing through the abnormal vessels of the tumor and the transition from normal to abnormal brain tissue.

Typically, intraoperative diagnosis is performed by obtaining several specimens from within a brain tumor using biopsy forceps and cutting, freezing and staining the specimen for examination under the microscope. The traditional analysis is limited by sampling error and by mechanical tissue damage from the biopsy forceps, slowing operative workflow by 30 to 40 minutes.

The new microscope can overcome these limitations by helping to visualize the cellular and tissue features of a tumor in real-time. As in the study, the probe can be moved over the entire visible extent of a tumor, guiding the neurosurgeon to hypercellular or aggressive areas that are likely to generate high-yield biopsies.

"As neuropathologists become familiar with the new confocal microscopic appearance of various tumor types and grades, the traditional intraoperative diagnosis may be replaced by the real-time analysis of confocal images by the new microscope," says Mark Preul, MD, Newsome Chair of Neurosurgery Research at Barrow. These images could be analyzed remotely, improving the accuracy of intraoperative diagnosis.

This study was presented at the Annual Meeting of the American Association of Neurological Surgeons in San Diego and was recently published in the Journal of Neurosurgery.


Story Source:

The above story is based on materials provided by St. Joseph's Hospital and Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

St. Joseph's Hospital and Medical Center. "New way to biopsy brain tumors in real time." ScienceDaily. ScienceDaily, 14 November 2009. <www.sciencedaily.com/releases/2009/11/091111153804.htm>.
St. Joseph's Hospital and Medical Center. (2009, November 14). New way to biopsy brain tumors in real time. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2009/11/091111153804.htm
St. Joseph's Hospital and Medical Center. "New way to biopsy brain tumors in real time." ScienceDaily. www.sciencedaily.com/releases/2009/11/091111153804.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins