Featured Research

from universities, journals, and other organizations

Researchers studying deep brain stimulation for Parkinson's disease

Date:
February 1, 2010
Source:
Scott & White Healthcare
Summary:
A multi-disciplinary team of neurosurgeons, neurologists, neurophysiologist, neuropsychologists and a movement disorders specialist are offering hope to some Parkinson's patients with a treatment called deep brain simulation.

At Scott & White Memorial Hospital, a multi-disciplinary team of neurosurgeons, neurologists, neurophysiologist, neuropsychologists and a movement disorders specialist are offering hope to some Parkinson's patients with a treatment called Deep Brain Stimulation (DBS).

DBS involves placing a thin wire that carries electrical currents deep within the brain on Parkinson's patients who are no longer benefitting from medications, and have significant uncontrollable body movements called dyskinesia.

Scott & White is also performing research into the effects of DBS on the non-motor symptoms of Parkinson's disease including "drenching sweats," bladder dysfunction, depression, hallucination, anxiety, and dementia as well as intestinal disorders, loss of sense of smell, and sleep disturbances.

"We've found that some Parkinson's patients experienced non-motor symptoms up to 20 to 30 years before their Parkinson's diagnosis, which leads us to believe the presence of these symptoms could be used as predictors of the onset of Parkinson's," said Manjit K Sanghera Ph.D. neurophysiologist at Scott & White and associate professor and director of the Human Electrophysiology Lab, Texas A&M Health Science Center College of Medicine. "If we're better able to identify individuals who are at high risk for Parkinson's, we can engage these patients in neuro-protective therapies, including exercise and medication." Dr. Sanghera's research is funded by the Plummer Foundation.

Parkinson's disease (PD) is a brain disorder that occurs when certain nerve cells or neurons in the brain die. When this happens, these cells no longer produce a chemical called dopamine, which facilitates the smooth, coordinated function of our muscles. When about 80% of these neurons die, that's when Parkinson's makes an appearance. The tell-tale signs include tremors, slowness of movement, rigidity, difficulty with balance, small, cramped handwriting, stiff facial expressions, a shuffling walk, and muffled speech.

"First-line medication works quite well for some time after diagnosis, sometimes a patient's lifetime, but typically a patient will need more and more medication over time to control their Parkinson's," said Gerhard Friehs, M.D., interim chairman of neurosurgery at Scott & White. "As the disease progresses and potentially becomes disabling, a treatment like Deep Brain Stimulation can provide significant improvement to a patient's quality of life."

DBS works by inactivating parts of the brain that cause Parkinson's disease and its associated symptoms without purposefully destroying the brain where electrodes are placed in the globus pallidus or subthalmic nucleus. "These electrodes are connected by wires to a type of pacemaker device implanted under the skin of the chest, below the collarbone, said Dr. Friehs. Once activated, the device sends continuous electrical impulses to the target areas in the brain, blocking the impulses that cause tremors, which can be turned on or off by the patient."

As with any surgical procedure, there are risks with DBS. There is a two to three percent risk of a serious and permanent complication such as paralysis, changes in cognition, memory and personality, seizures and infection.


Story Source:

The above story is based on materials provided by Scott & White Healthcare. Note: Materials may be edited for content and length.


Cite This Page:

Scott & White Healthcare. "Researchers studying deep brain stimulation for Parkinson's disease." ScienceDaily. ScienceDaily, 1 February 2010. <www.sciencedaily.com/releases/2010/01/100126153425.htm>.
Scott & White Healthcare. (2010, February 1). Researchers studying deep brain stimulation for Parkinson's disease. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2010/01/100126153425.htm
Scott & White Healthcare. "Researchers studying deep brain stimulation for Parkinson's disease." ScienceDaily. www.sciencedaily.com/releases/2010/01/100126153425.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com
Hundreds in Virginia Turn out for a Free Clinic to Manage Health

Hundreds in Virginia Turn out for a Free Clinic to Manage Health

AFP (July 24, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th - prompting hundreds in Virginia to turn out for a free clinic run by “Remote Area Medical”. Duration 02:40 Video provided by AFP
Powered by NewsLook.com
Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins