Featured Research

from universities, journals, and other organizations

Infertility increases a man's risk of prostate cancer

Date:
March 22, 2010
Source:
American Cancer Society
Summary:
Infertile men have an increased risk of developing high grade prostate cancer, which is more likely to grow and spread quickly, a new study has found.

Infertile men have an increased risk of developing high grade prostate cancer, which is more likely to grow and spread quickly. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society.

Related Articles


The study's results suggest that because infertility may be an identifiable risk factor for prostate cancer, early screening may be warranted in infertile men.

Research focusing on the number of children a man has have pointed to male fertility's potential associated with risk for prostate cancer. However, studies on the topic have generated conflicting results: some have found that men with children had a higher risk than childless men; some have found that men with fewer children had a higher risk than men with more children; still others failed to identify any association between the number of children fathered and a man's risk for prostate cancer.

Because the number of children a man has may not accurately reflect his ability to cause a pregnancy, Thomas Walsh, MD, MS, of the University of Washington in Seattle and his colleagues designed a more accurate study to evaluate the association between male infertility and prostate cancer. They studied the risk for prostate cancer in a group of 22,562 men evaluated for infertility from 1967 to 1998 in 15 California infertility centers. The incidence of prostate cancer in these men was compared with the incidence in a sample of men in the general population who were of similar ages and from similar geographic locations.

The researchers identified 168 cases of prostate cancer that developed in men who were evaluated for infertility. That number not significantly different from the expected rate (185 cases), suggesting that overall, men evaluated for infertility were not at a higher risk of being diagnosed with any type of prostate cancer compared with men in the general population. However, men who were evaluated and found to be infertile were 2.6 times more likely to be diagnosed with high grade prostate cancer than men who were evaluated but were found not to be infertile.

The authors say if these results are confirmed in other studies, it may be appropriate for infertile men to be considered for early prostate cancer screening, given their elevated risk for aggressive disease. They add that the results should stimulate research on possible common biological pathways underlying infertility and prostate cancer.


Story Source:

The above story is based on materials provided by American Cancer Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Thomas J. Walsh, Michael Schembri, Paul J. Turek, June M. Chan, Peter R. Carroll, James F. Smith, Michael L. Eisenberg, Stephen K. Van Den Eeden, and Mary S. Croughan. Increased risk of high grade prostate cancer among infertile men. Cancer, 2010; DOI: 10.1002/cncr.25075

Cite This Page:

American Cancer Society. "Infertility increases a man's risk of prostate cancer." ScienceDaily. ScienceDaily, 22 March 2010. <www.sciencedaily.com/releases/2010/03/100322073530.htm>.
American Cancer Society. (2010, March 22). Infertility increases a man's risk of prostate cancer. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2010/03/100322073530.htm
American Cancer Society. "Infertility increases a man's risk of prostate cancer." ScienceDaily. www.sciencedaily.com/releases/2010/03/100322073530.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins