Featured Research

from universities, journals, and other organizations

Diesel exhaust associated with lethargy in offspring

Date:
March 24, 2010
Source:
BioMed Central
Summary:
Breathing diesel exhaust during pregnancy is associated with sluggishness in offspring. Researchers studied the effects of pollution exposure in mice, finding that the offspring of mothers who breathed diesel fumes while pregnant were less likely to show spontaneous movement.

Breathing diesel exhaust during pregnancy is associated with sluggishness in offspring. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology studied the effects of pollution exposure in mice, finding that the offspring of mothers who breathed diesel fumes while pregnant were less likely to show spontaneous movement.

Ken Takeda, from Tokyo University of Science, Japan, worked with a team of researchers to carry out the study in pregnant mice, randomly assigned to be exposed to diesel exhaust or filtered air. He said, "We then took ten random male pups from each group and monitored their movement at 10 minute intervals for 3 days. We found that the mice whose mothers had breathed the fumes showed significantly less spontaneous motor activity and that this inactivity was associated with alterations in brain metabolism of neurotransmitters."

Spontaneous movement rates are a validated model for measuring the effect of brain activity or neural transmission to peripheral muscles. For instance tranquilizers are known to diminish brain activity and this leads to a decrease in movement. The researchers speculate that certain components, such as ultrafine particles, in the diesel exhaust may be translocated into the offspring of mice, disturbing the normal timetable of development in offspring and leading to the behavioral and physiological abnormalities seen in this study. Alternatively, or additionally, diesel exhaust exposure may affect the mother's behavior toward the pups after birth, which could also cause lethargy and altered brain chemistry.

Takeda concludes, "Further investigations are needed to clarify the critical factors or components responsible for the effects on offspring. Since the concentration of diesel exhaust we used was close to the environmental quality standard of air in Japan, these findings warrant a revisiting of present pollution standards in each country of the world."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tomoharu Suzuki, Shigeru Oshio, Mari Iwata, Hisayo Saburi, Takashi Odagiri, Tadashi Udagawa, Isamu Sugawara, Masakazu Umezawa and Ken Takeda. In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice. Particle and Fibre Toxicology, 2010; 7: 7 DOI: 10.1186/1743-8977-7-7

Cite This Page:

BioMed Central. "Diesel exhaust associated with lethargy in offspring." ScienceDaily. ScienceDaily, 24 March 2010. <www.sciencedaily.com/releases/2010/03/100323105943.htm>.
BioMed Central. (2010, March 24). Diesel exhaust associated with lethargy in offspring. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2010/03/100323105943.htm
BioMed Central. "Diesel exhaust associated with lethargy in offspring." ScienceDaily. www.sciencedaily.com/releases/2010/03/100323105943.htm (accessed September 19, 2014).

Share This



More Earth & Climate News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Wildfires in CA Burn Forest Asunder

Raw: Wildfires in CA Burn Forest Asunder

AP (Sep. 18, 2014) An out-of-control Northern California wildfire has nearly 2,800 people from their homes as it continues to grow, authorities said Thursday. Authorities said a man has been arrested on suspicion of arson for starting the fire on Saturday. (Sept. 18) Video provided by AP
Powered by NewsLook.com
Raw: Elephant Undergoes Surgery in Tbilisi Zoo

Raw: Elephant Undergoes Surgery in Tbilisi Zoo

AP (Sep. 18, 2014) Grand the elephant has successfully undergone surgery to remove a portion of infected tusk at Tbilisi Zoo in Georgia. British veterinary surgeons used an electric drill to extract the infected piece. (Sept. 18) Video provided by AP
Powered by NewsLook.com
Raw: Scientists Examine Colossal Squid

Raw: Scientists Examine Colossal Squid

AP (Sep. 16, 2014) Squid experts in New Zealand thawed and examined an unusual catch on Tuesday: a colossal squid. It was captured in Antarctica's remote Ross Sea in December last year and has been frozen for eight months. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins