Featured Research

from universities, journals, and other organizations

Valuable baseline data of recent hepatitis A in Asian area

Date:
March 30, 2010
Source:
World Journal of Gastroenterology
Summary:
There has been an apparent epidemiological shift in hepatitis A virus seroprevalence and a change in the peak age of HAV hepatitis in Korea, and the cases of acute hepatitis A have increased rapidly during the past 10 years due to the emergence of susceptible adults. A research group in South Korea provided valuable baseline data of recent hepatitis A in an Asian area with an epidemiological shift.

In Korea, there has been a rapid epidemiological shift in hepatitis A virus (HAV) infection as a result of rapid economic development. The adult cases of acute hepatitis A have increased rapidly during the past 10 years due to the emergence of susceptible adults in Korea.

After 2000, symptomatic cases of HAV infection markedly increased and the age of affected patients was significantly higher before 2000 than after 2000. This transitional pattern also has been reported in other Asian populations that have similar environmental conditions. A research article be published on March 7, 2010 in the World Journal of Gastroenterology evaluated seroprevalence of total HAV antibody, with large-scale data, and investigated demographic, clinical, and laboratory features of recent cases of HAV in Korea, where there is an ongoing epidemiological shift.

Among 3127 sera tested, 1428 were positive for total anti-HAV antibody. The seroprevalence was very low in patients in their teens or twenties, increased in those in their thirties, and was > 90% in older patients. In children younger than 10 years, seroprevalence was increased again. Most patients with HAV hepatitis were in their twenties and thirties. -glutamyl transpeptidase increased with age and was significantly higher in patients older than 30 years. Indicators of severity, such as decreased albumin and increased bilirubin, were also more prominent in the older age group; however, the leukocyte count was higher and the frequency of leukopenia was lower in the younger group than in older adults.

In the study, seroprevalence increased with age and showed an abrupt rise in patients older than 30 years of age compared to those younger than 30 years. These results are consistent with other recent studies in Korea. This is thought to be due to different epidemiological and socioeconomic environments during the economic development of Korea. Of note, with the recent increase of HAV vaccination in childhood, there has been an apparent epidemiological shift in HAV seroprevalence and a change in the peak age of HAV hepatitis. In the study, most patients with HAV were in their twenties and thirties and most were male. The male predominance was especially true of patients in their thirties, which may be due to more exposure to the virus in men of that age. These cases revealed a severe pattern of acute hepatitis. And the study could provide valuable baseline data of recent hepatitis A in an Asian area with an epidemiological shift.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Moon et al. Laboratory characteristics of recent hepatitis A in Korea: Ongoing epidemiological shift. World Journal of Gastroenterology, 2010; 16 (9): 1115 DOI: 10.3748/wjg.v16.i9.1115

Cite This Page:

World Journal of Gastroenterology. "Valuable baseline data of recent hepatitis A in Asian area." ScienceDaily. ScienceDaily, 30 March 2010. <www.sciencedaily.com/releases/2010/03/100330102745.htm>.
World Journal of Gastroenterology. (2010, March 30). Valuable baseline data of recent hepatitis A in Asian area. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2010/03/100330102745.htm
World Journal of Gastroenterology. "Valuable baseline data of recent hepatitis A in Asian area." ScienceDaily. www.sciencedaily.com/releases/2010/03/100330102745.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins