Featured Research

from universities, journals, and other organizations

Association of fiber and colorectal cancer risk differs depending on dietary assessment method

Date:
April 20, 2010
Source:
Journal of the National Cancer Institute
Summary:
High dietary fiber intake was associated with a lower risk of colorectal cancer when researchers used data from food diaries but not when they used data obtained from food frequency questionnaires, according to a new study.

High dietary fiber intake was associated with a lower risk of colorectal cancer when researchers used data from food diaries but not when they used data obtained from food frequency questionnaires, according to a study published online April 20 in the Journal of the National Cancer Institute.

Related Articles


Previous studies have examined the issue of dietary fiber and risk of colorectal cancer, but the results have been inconsistent, particularly in studies that used food-frequency questionnaires (FFQs).

In this study, Christina Dahm Ph.D., and Kay-Tee Khaw, MBBChir., of the University of Cambridge in the UK, and colleagues used data obtained from both food diaries and food frequency questionnaires to estimate fiber intake. Their prospective, case-control study was nested within seven UK cohort studies and included 579 patients who developed colorectal cancer more than 1 year after they began keeping the food diaries. These case patients' fiber intake was compared with that of 1,996 control subjects who did not develop colorectal cancer. Case and control subjects were matched for sex, age, and date of diary completion.

The researchers found that participants who had higher intakes of fiber, ascertained by food diaries, were less likely to develop colorectal cancer than those with lower intakes. For individuals who consumed an average of 24 grams per day of dietary fiber, the odds of developing colorectal cancer were 30% lower than for those who consumed an average 10 grams per day. The difference was statistically significant and consistent even after the researchers took into account other risk factors for colorectal cancer, such as age, physical activity, and intakes of alcohol and red meats.

However, when the researchers performed the same analysis using data obtained from the food frequency questionnaires, they found no statistically significant association between fiber intake and the risk of colorectal cancer.

"These findings strengthen existing evidence that supports recommendations to increase dietary fiber intake in populations to reduce colorectal cancer incidence," the authors write. They suggest that "the fact that we found no association using…the FFQ may explain the lack of convincing evidence relating fiber intake to a substantial reduction in colorectal cancer risk in some previous studies that relied on FFQs."

In an accompanying editorial, Ross Prentice, Ph.D., of the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, notes that accurate measurement of dietary components remains a major challenge in studies of diet and cancer risk. He calls for the development of biological markers to measure intake more accurately. "The explicit use of biomarkers to correct nutritional epidemiology associations for systematic and random measurement error in dietary assessment seems a logical next step in the nutritional epidemiology research agenda," he writes.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Christina C. Dahm, Ruth H. Keogh, Elizabeth A. Spencer, Darren C. Greenwood, Tim J. Key, Ian S. Fentiman, Martin J. Shipley, Eric J. Brunner, Janet E. Cade, Victoria J. Burley, Gita Mishra, Alison M. Stephen, Diana Kuh, Ian R. White, Robert Luben, Marleen A. H. Lentjes, Kay Tee Khaw, and Sheila A. Rodwell (Bingham). Dietary Fiber and Colorectal Cancer Risk: A Nested Case-Control Study Using Food Diaries. Journal of the National Cancer Institute, April 20, 2010. DOI: 10.1093/jnci/djq092

Cite This Page:

Journal of the National Cancer Institute. "Association of fiber and colorectal cancer risk differs depending on dietary assessment method." ScienceDaily. ScienceDaily, 20 April 2010. <www.sciencedaily.com/releases/2010/04/100420161756.htm>.
Journal of the National Cancer Institute. (2010, April 20). Association of fiber and colorectal cancer risk differs depending on dietary assessment method. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2010/04/100420161756.htm
Journal of the National Cancer Institute. "Association of fiber and colorectal cancer risk differs depending on dietary assessment method." ScienceDaily. www.sciencedaily.com/releases/2010/04/100420161756.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins