Featured Research

from universities, journals, and other organizations

Testosterone deficiency in childhood cancer survivors

Date:
June 3, 2010
Source:
Lund University
Summary:
Almost a quarter of men treated for cancer in their childhood suffer from a deficiency of the male sex hormone testosterone. The deficiency can be treated with hormone supplements if the problem is diagnosed. However, this happens all too rarely, as new research shows.

Almost a quarter of men treated for cancer in their childhood suffer from a deficiency of the male sex hormone testosterone. The deficiency can be treated with hormone supplements if the problem is diagnosed. However, this happens all too rarely, as doctor Patrik Romerius shows in his thesis.

Related Articles


Testosterone deficiency not only affects sex drive: in the long term it can lead to depression, reduced muscle strength, osteoporosis, type 2 diabetes, high blood pressure and cardiovascular diseases.

"But if a young man comes to the health centre and complains of low libido and depression, this might be explained as the psychological effects of the cancer he had when he was younger. In actual fact it may be due to a hormone reduction that can be treated," says Patrik Romerius.

In one of his studies he examined 150 men who had been treated for leukaemia and other forms of cancer before reaching adulthood. He found that 33 of them had testosterone deficiency, but that this had only been diagnosed in 4 cases. Patrik Romerius believes that the reason for this is that it is a new patient group.

"Just a few decades ago, very few childhood cancer patients survived. Now almost 4 in 5 recover as a result of better diagnosis and treatment methods. But it is only now that the large groups of childhood cancer survivors have reached an age where the consequences of the treatment are starting to be seen," he says.

The majority of the former cancer patients who were suffering from hormone deficiency were also infertile because the cancer treatment had impaired their sperm production. During and after puberty, young men can provide sperm samples that are frozen and saved, but before puberty, boys do not produce sperm. The only option then is to remove testicular tissue to be preserved for the future.

Today it is not possible to extract sperm from such tissue, but this has been achieved in animal experiments and could become possible in humans in the future. However, removing testicular tissue involves a separate operation before the actual cancer treatment -- a further strain for the young cancer patient.

The research group has produced a genetic marker that makes it possible, by means of a simple blood test, to identify which patients are at highest risk of losing their sperm production entirely and should therefore be offered the operation.


Story Source:

The above story is based on materials provided by Lund University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Male reproductive function in long-term survivors of childhood cancer. Journal of Clinical Endocrinology and Metabolism, 2009

Cite This Page:

Lund University. "Testosterone deficiency in childhood cancer survivors." ScienceDaily. ScienceDaily, 3 June 2010. <www.sciencedaily.com/releases/2010/06/100603091933.htm>.
Lund University. (2010, June 3). Testosterone deficiency in childhood cancer survivors. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2010/06/100603091933.htm
Lund University. "Testosterone deficiency in childhood cancer survivors." ScienceDaily. www.sciencedaily.com/releases/2010/06/100603091933.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins