Featured Research

from universities, journals, and other organizations

Testosterone deficiency in childhood cancer survivors

Date:
June 3, 2010
Source:
Lund University
Summary:
Almost a quarter of men treated for cancer in their childhood suffer from a deficiency of the male sex hormone testosterone. The deficiency can be treated with hormone supplements if the problem is diagnosed. However, this happens all too rarely, as new research shows.

Almost a quarter of men treated for cancer in their childhood suffer from a deficiency of the male sex hormone testosterone. The deficiency can be treated with hormone supplements if the problem is diagnosed. However, this happens all too rarely, as doctor Patrik Romerius shows in his thesis.

Testosterone deficiency not only affects sex drive: in the long term it can lead to depression, reduced muscle strength, osteoporosis, type 2 diabetes, high blood pressure and cardiovascular diseases.

"But if a young man comes to the health centre and complains of low libido and depression, this might be explained as the psychological effects of the cancer he had when he was younger. In actual fact it may be due to a hormone reduction that can be treated," says Patrik Romerius.

In one of his studies he examined 150 men who had been treated for leukaemia and other forms of cancer before reaching adulthood. He found that 33 of them had testosterone deficiency, but that this had only been diagnosed in 4 cases. Patrik Romerius believes that the reason for this is that it is a new patient group.

"Just a few decades ago, very few childhood cancer patients survived. Now almost 4 in 5 recover as a result of better diagnosis and treatment methods. But it is only now that the large groups of childhood cancer survivors have reached an age where the consequences of the treatment are starting to be seen," he says.

The majority of the former cancer patients who were suffering from hormone deficiency were also infertile because the cancer treatment had impaired their sperm production. During and after puberty, young men can provide sperm samples that are frozen and saved, but before puberty, boys do not produce sperm. The only option then is to remove testicular tissue to be preserved for the future.

Today it is not possible to extract sperm from such tissue, but this has been achieved in animal experiments and could become possible in humans in the future. However, removing testicular tissue involves a separate operation before the actual cancer treatment -- a further strain for the young cancer patient.

The research group has produced a genetic marker that makes it possible, by means of a simple blood test, to identify which patients are at highest risk of losing their sperm production entirely and should therefore be offered the operation.


Story Source:

The above story is based on materials provided by Lund University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Male reproductive function in long-term survivors of childhood cancer. Journal of Clinical Endocrinology and Metabolism, 2009

Cite This Page:

Lund University. "Testosterone deficiency in childhood cancer survivors." ScienceDaily. ScienceDaily, 3 June 2010. <www.sciencedaily.com/releases/2010/06/100603091933.htm>.
Lund University. (2010, June 3). Testosterone deficiency in childhood cancer survivors. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2010/06/100603091933.htm
Lund University. "Testosterone deficiency in childhood cancer survivors." ScienceDaily. www.sciencedaily.com/releases/2010/06/100603091933.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Obama: Ebola Outbreak Threat to Global Security

Obama: Ebola Outbreak Threat to Global Security

AP (Sep. 16, 2014) President Obama is ordering U.S. military personnel to West Africa to deal with the Ebola outbreak, which is he calls a potential threat to global security. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins