Featured Research

from universities, journals, and other organizations

Molecular imaging agent coupled with 'motion frozen' processing improves heart imaging

Date:
June 7, 2010
Source:
Society of Nuclear Medicine
Summary:
Molecular imaging of the heart just got better, according to a new study. Combining a potential new imaging agent with a molecular imaging technique that reduces blur caused by the motion of the heart and lungs could lead to unprecedented image quality when conducting myocardial perfusion imaging, a procedure used to evaluate blood flow to the heart.

Molecular imaging of the heart just got better, according to a study revealed at the Society of Nuclear Medicine's 57th Annual Meeting. Combining a potential new imaging agent with a molecular imaging technique that reduces blur caused by the motion of the heart and lungs could lead to unprecedented image quality when conducting myocardial perfusion imaging, a procedure used to evaluate blood flow to the heart.

Related Articles


"Both cardiac and respiratory motion degrade image quality by adding some unwanted blur," said Ludovic Le Meunier, Ph.D., lead researcher and staff scientist for Siemens Healthcare, Knoxville, Tenn., based at Cedars-Sinai Medical Center, Los Angeles, Calif. "Our objective in this work was to provide the highest myocardial perfusion image quality by using a promising heart imaging agent and correcting the motion of those organs. In conjunction, these tools can provide unprecedented diagnostic capability for clinicians evaluating heart disease."

The new imaging agent, called flurpiridaz F 18 injection, uses a fluorine-18 (F-18) based radioisotope, and while it is still in clinical trials, the compound has been shown to facilitate very high-quality imaging of the heart. Other positron emission tomography (PET) agents used to image the heart have a much shorter half-life and need to be produced within an on-site cyclotron, which limits access. Some agents can be produced on-site with a generator, but image quality appears not to be as high. F-18 has a half-life of 108 minutes and therefore can be delivered to imaging centers located within a wider radius, with no compromise to image quality.

The technology used in this study included high-definition, or "HD" PET, a technique that images the body's physiological functions and automatically corrects distortions that occur during scanning. Next, researchers used post-scan image processing tools called respiratory gating and "motion-frozen" cardiac gating, which cut out or otherwise compensate for the motion of these organs during scanning. The result is virtually motion-free myocardial perfusion imaging.

This clinical trial was led by Daniel Berman, M.D., director of cardiac imaging and nuclear cardiology at Cedars-Sinai Medical Center. Motion-frozen technology was developed in collaboration with Piotr Slomka, Ph.D., a research scientist at Cedars-Sinai and professor of medicine at the University of California, Los Angeles.

Scientific Paper 522: L. Le Meunier, Siemens Healthcare, Knoxville, Tenn.; P.J. Slomka, A. Ramesh, L.E. Thomson, S.W. Hayes, B. Tamarappoo, V. Cheng, G. Germano, D.S. Berman, Cedars-Sinai Medical Center, Los Angeles, Calif.; J. Lazewatsky, Lantheus Medical Imaging, North Billerica, Mass.; "Enhanced dual gated cardiac perfusion PET using a new F-18 imaging agent (BMS747158)," SNM's 57th Annual Meeting, June 5-9, 2010, Salt Lake City, Utah.


Story Source:

The above story is based on materials provided by Society of Nuclear Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society of Nuclear Medicine. "Molecular imaging agent coupled with 'motion frozen' processing improves heart imaging." ScienceDaily. ScienceDaily, 7 June 2010. <www.sciencedaily.com/releases/2010/06/100607142007.htm>.
Society of Nuclear Medicine. (2010, June 7). Molecular imaging agent coupled with 'motion frozen' processing improves heart imaging. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2010/06/100607142007.htm
Society of Nuclear Medicine. "Molecular imaging agent coupled with 'motion frozen' processing improves heart imaging." ScienceDaily. www.sciencedaily.com/releases/2010/06/100607142007.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins