Featured Research

from universities, journals, and other organizations

The evolution of melanoma diagnosis: 25 years beyond the ABCDs

Date:
July 29, 2010
Source:
American Cancer Society
Summary:
Twenty-five years after publishing the mnemonic "ABCD" to facilitate the early diagnosis of melanoma, the group who came up with that moniker says early detection remains a key factor in lowering mortality from malignant melanoma.

Twenty-five years after publishing the mnemonic "ABCD" to facilitate the early diagnosis of melanoma, the group who came up with that moniker says early detection remains a key factor in lowering mortality from malignant melanoma. Darrell S. Rigel, M.D. and colleagues from the Ronald O. Perelman Department of Dermatology at New York University School of Medicine say that, despite all of the advances in melanoma diagnosis, timely recognition, detection, and rapid treatment of melanoma remain critical. Their report appears online on CA First Look, and will appear in the September/October issue of CA: A Cancer Journal for Clinicians.

Although examining tumor cells under a microscope remains the gold standard for diagnosing melanoma, it is one of very few cancers that has the potential to be diagnosed at an early stage through noninvasive approaches because it appears on the outside of the body. Based on their experience in evaluating patients at the New York University School of Medicine Melanoma Cooperative Group, the authors of the current report recommended in 1985 that attention to asymmetry (A), border irregularity (B), color variegation (C), and diameter more than 6 mm (D) of pigmented skin lesions could promote earlier recognition of malignant melanoma.

Approaches to melanoma diagnosis have dynamically evolved during the ensuing quarter century. In the 1990s, dermoscopy enabled the recognition of new subsurface features to help differentiate between malignant and benign pigmented lesions. During the last decade, new computer-based technologies have improved diagnostic sensitivity and specificity and may result in optimizing lesion selection for biopsy and pathology review.

"From the development of the ABCDs through current attempts that use complex computer algorithms and genetic markers, a clinician's ability to detect melanoma in its earliest form has been augmented," write the authors. "However, a 'good clinical eye' is still fundamental to selecting the lesions for evaluation among the sea of those that are prevalent."


Story Source:

The above story is based on materials provided by American Cancer Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Darrell S. Rigel, MD; Julie Russak, MD; Robert Friedman, MD. The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs. CA Cancer J Clin, July 28, 2010 DOI: 10.3322/caac.20074

Cite This Page:

American Cancer Society. "The evolution of melanoma diagnosis: 25 years beyond the ABCDs." ScienceDaily. ScienceDaily, 29 July 2010. <www.sciencedaily.com/releases/2010/07/100729122328.htm>.
American Cancer Society. (2010, July 29). The evolution of melanoma diagnosis: 25 years beyond the ABCDs. ScienceDaily. Retrieved September 14, 2014 from www.sciencedaily.com/releases/2010/07/100729122328.htm
American Cancer Society. "The evolution of melanoma diagnosis: 25 years beyond the ABCDs." ScienceDaily. www.sciencedaily.com/releases/2010/07/100729122328.htm (accessed September 14, 2014).

Share This



More Health & Medicine News

Sunday, September 14, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
Contagious Respiratory Illness Continues to Spread Across U.S.

Contagious Respiratory Illness Continues to Spread Across U.S.

Reuters - US Online Video (Sep. 12, 2014) Hundreds of children in several states have been stricken by a serious respiratory illness that is spreading across the U.S. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Batters Sierra Leone Economy Too

Ebola Batters Sierra Leone Economy Too

Reuters - Business Video Online (Sep. 12, 2014) The World Health Organisation warns that local health workers in West Africa can't keep up with Ebola - and among those countries hardest hit by the outbreak, the economic damage is coming into focus, too. As David Pollard reports, Sierra Leone admits that growth in one of the poorest economies in the region is taking a beating. Video provided by Reuters
Powered by NewsLook.com
Health Care Workers 'Chasing' Ebola Outbreak

Health Care Workers 'Chasing' Ebola Outbreak

Newsy (Sep. 12, 2014) The worst known Ebola outbreak is proving extremely difficult to contain. Hospitals are full, and victims of the virus are suffering in the streets. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins