Featured Research

from universities, journals, and other organizations

Deep Brain Stimulation shows promise for patients with Alzheimer's

Date:
August 6, 2010
Source:
University Health Network
Summary:
Using deep brain stimulation on patients with early signs of Alzheimer's disease is safe and may help improve memory, medical researchers say.

In a world first, Dr. Andres M. Lozano and his team at Toronto Western Hospital has shown using Deep Brain Stimulation (DBS) on patients with early signs of Alzheimer's disease is safe and may help improve memory.

The phase one safety trial of six Ontario patients took place from 2005 to 2008. All patients left hospital within 2 to 3 days of surgery, and continue to participate in regular follow-up cognitive assessments.

Throughout these assessments, Dr. Lozano says half the patients continue to perform better than predicted -- that is -- their memory capacity has improved, or deteriorated less than expected.

"While the study was not looking for efficacy, the results suggest that of the six patients, three may have done better than if the Alzheimer's disease was allowed to run its course," commented Lozano. "We showed that not only is this a safe procedure, but that the evidence is there to warrant a bigger trial. Any amount of time that extends quality of life and quality years to someone with Alzheimer's may be a benefit."

Dr. Lozano first discovered the potential for DBS to treat Alzheimer's disease while treating a patient for obesity using DBS back in 2003. While signaling areas of the brain, Dr. Lozano and his team triggered memories in the patient. In follow-up testing the patient's memory improved and Dr. Lozano set in motion the first ever DBS trial of patients with early signs of Alzheimer's disease.

"We've demonstrated this is safe, and that the evidence warrants more study. We're now planning a phase two, multi-centred trial -- we're just waiting on the funding," says Dr. Lozano.

Results of Dr. Lozano's trial are published in the August 4 issue of Annals of Neurology.


Story Source:

The above story is based on materials provided by University Health Network. Note: Materials may be edited for content and length.


Journal Reference:

  1. Adrian W. Laxton, David F. Tang-Wai, Mary Pat McAndrews, Dominik Zumsteg, Richard Wennberg, Ron Keren, John Wherrett, Gary Naglie, Clement Hamani, Gwenn S. Smith, Andres M. Lozano. A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease. Annals of Neurology, August 4, 2010 DOI: 10.1002/ana.22089

Cite This Page:

University Health Network. "Deep Brain Stimulation shows promise for patients with Alzheimer's." ScienceDaily. ScienceDaily, 6 August 2010. <www.sciencedaily.com/releases/2010/08/100804122707.htm>.
University Health Network. (2010, August 6). Deep Brain Stimulation shows promise for patients with Alzheimer's. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2010/08/100804122707.htm
University Health Network. "Deep Brain Stimulation shows promise for patients with Alzheimer's." ScienceDaily. www.sciencedaily.com/releases/2010/08/100804122707.htm (accessed September 17, 2014).

Share This



More Mind & Brain News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Corporal Punishment on Decline, Debate Renews

Corporal Punishment on Decline, Debate Renews

AP (Sep. 16, 2014) Corporal punishment in the United States is on the decline, but there is renewed debate over its use after Minnesota Vikings running back Adrian Peterson was charged with child abuse. (Sept. 16) Video provided by AP
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
'Magic Mushrooms' Could Help Smokers Quit

'Magic Mushrooms' Could Help Smokers Quit

Newsy (Sep. 11, 2014) In a small study, researchers found that the majority of long-time smokers quit after taking psilocybin pills and undergoing therapy sessions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins