Featured Research

from universities, journals, and other organizations

Discovery may help identify the healthiest embryos in IVF treatment

Date:
November 1, 2010
Source:
University of Melbourne
Summary:
Australian scientists have developed a potentially groundbreaking new measure of the health of an embryo and the likelihood of a successful pregnancy in IVF treatment.

Australian scientists have developed a potentially groundbreaking new measure of the health of an embryo and the likelihood of a successful pregnancy in IVF treatment.

The research could lead to significantly improved birth rates in IVF to help the one in six Australian couples experiencing infertility to achieve their dream of parenthood.

It also has the potential to predict the gender of an embryo prior to implantation.

The study conducted by the University of Melbourne and Repromed is being presented at the Fertility Society of Australia annual scientific meeting at the Adelaide Convention Centre.

Professor David Gardner, Head of the Department of Zoology at the University of Melbourne, said the study related specifically to the glucose intake of embryos from the solution in which they grow in the laboratory.

IVF units use this solution, or media as it is known, to provide a bed of nutrients for embryos fertilised in the laboratory from the eggs and sperm of couples who cannot naturally conceive. The glucose in embryo solution closely matches that which occurs naturally in the uterus.

Professor Gardner said fertility specialists knew the precise amount of glucose in the solution before inserting an embryo.

"By measuring the level of glucose on day four or five after fertilisation, we can determine how much has been consumed by a growing embryo," he explained. "There is clear cut evidence that the greater the glucose intake the healthier the embryo.

"On average, IVF units generate between eight and ten embryos per cycle, of which about half will progress through cell division to what is known as the blastocyst stage after four to five days.

"By measuring the glucose consumption of an embryo, we can better determine which is the healthiest embryo for transfer back to the patient."

The research involved 50 patients undergoing IVF. Thirty-two of the women had a positive pregnancy test after embryo transfer and 28 babies were born.

"The 28 babies resulted from the embryos which had the highest glucose uptake," Professor Gardner said.

"Previous studies with animals have shown that the healthiest blastocysts are those with the greatest glucose consumption indicating the likelihood of a successful pregnancy.

"It is exciting to find that this process appears to be the same in people knowing that the glucose in embryo culture media is a major energy source for cell division and is required for biosynthesis to enable cell replication."

Professor Gardner said another potentially exciting aspect of the research was that female embryos appeared to take up more glucose than male embryos.

"This is a very early observation, but it may have the potential to help identify gender at early embryo stage," he said.

World leaders in assisted reproduction have gathered in Adelaide to explore latest research and clinical treatments to help couples experiencing infertility, which is defined as the failure to conceive after a year of unprotected intercourse, or the inability to carry pregnancies to a live birth.


Story Source:

The above story is based on materials provided by University of Melbourne. Note: Materials may be edited for content and length.


Cite This Page:

University of Melbourne. "Discovery may help identify the healthiest embryos in IVF treatment." ScienceDaily. ScienceDaily, 1 November 2010. <www.sciencedaily.com/releases/2010/10/101012101617.htm>.
University of Melbourne. (2010, November 1). Discovery may help identify the healthiest embryos in IVF treatment. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2010/10/101012101617.htm
University of Melbourne. "Discovery may help identify the healthiest embryos in IVF treatment." ScienceDaily. www.sciencedaily.com/releases/2010/10/101012101617.htm (accessed April 16, 2014).

Share This



More Health & Medicine News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
How Mt. Everest Helped Scientists Research Diabetes

How Mt. Everest Helped Scientists Research Diabetes

Newsy (Apr. 15, 2014) British researchers were able to use Mount Everest's low altitudes to study insulin resistance. They hope to find ways to treat diabetes. Video provided by Newsy
Powered by NewsLook.com
Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Newsy (Apr. 14, 2014) Richard van As lost all fingers on his right hand in a woodworking accident. Now, he's used the incident to create a prosthetic to help hundreds. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins