Featured Research

from universities, journals, and other organizations

Brain bleeding is common with aging, study finds

Date:
November 9, 2010
Source:
University of California - Irvine
Summary:
A small amount of bleeding in the brain seems to be common among older individuals, according to a new study.

A small amount of bleeding in the brain seems to be common among older individuals, according to a UC Irvine study.

Related Articles


Neurologist Dr. Mark Fisher and neuropathologist Dr. Ronald Kim found that cerebral microbleeds are highly prevalent in the aging brain -- and not primarily products of stroke-related injury, hypertension or neurodegenerative diseases such as Alzheimer's, as had been thought.

"Prior work relied on brain imaging to show cerebral microbleeds," Fisher said. "But in this study, deep regions of the brain were closely examined under a microscope, and nearly all subjects had evidence of small areas of bleeding."

Results appear online in the journal Stroke.

Fisher, Kim and colleagues at Harbor-UCLA Medical Center studied postmortem brain specimens from 33 individuals, ranging in age from 71 to 105, with no history of stroke. Cerebral microbleeds were identified in 22 cases -- all occurring in capillaries, the small blood vessels of the brain.

This is a substantially higher rate of incidence than that reported in MRI studies, which have shown microbleeds in 18 percent of people between 60 and 69 and in 38 percent of those over 80.

"Drugs that interfere with platelets and blood clotting, such as aspirin, are known to be associated with microbleeds seen in brain imaging studies," Fisher said. "Our findings suggest that aspirin and other platelet medications may have a different effect on the aging brain than on younger brains."

Results from the UCI study also indicate that leakiness of brain blood vessels increases with age, he said, despite the fact that a specific barrier (known as the blood-brain barrier) exists to prevent leakiness.

The areas of bleeding found in the study were very small and certainly not life-threatening, Fisher said. How they might affect intellectual and neurological function is a subject for further exploration.

Dr. Samuel French and Dr. Ping Ji of Harbor-UCLA participated in the study, which received National Institutes of Health support.


Story Source:

The above story is based on materials provided by University of California - Irvine. Note: Materials may be edited for content and length.


Journal Reference:

  1. M. Fisher, S. French, P. Ji, R. C. Kim. Cerebral Microbleeds in the Elderly. A Pathological Analysis. Stroke, 2010; DOI: 10.1161/STROKEAHA.110.593657

Cite This Page:

University of California - Irvine. "Brain bleeding is common with aging, study finds." ScienceDaily. ScienceDaily, 9 November 2010. <www.sciencedaily.com/releases/2010/11/101108151340.htm>.
University of California - Irvine. (2010, November 9). Brain bleeding is common with aging, study finds. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2010/11/101108151340.htm
University of California - Irvine. "Brain bleeding is common with aging, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/11/101108151340.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins