Featured Research

from universities, journals, and other organizations

Common for patients to undergo multiple cardiac imaging tests, with high cumulative radiation dose

Date:
November 15, 2010
Source:
JAMA and Archives Journals
Summary:
Multiple testing with the cardiac diagnostic imaging technique of myocardial perfusion imaging is common, and in many patients is associated with a high cumulative estimated radiation dose, according to a new study.

Multiple testing with the cardiac diagnostic imaging technique of myocardial perfusion imaging is common, and in many patients is associated with a high cumulative estimated radiation dose, according to a study in the November 17 issue of JAMA.

Related Articles


Use of medical imaging has grown rapidly in recent years, but along with the potential benefits has come an increase in the amount of ionizing radiation associated with many such tests and the accompanying potential risks of cancer. "Although much attention has been paid to radiation from computed tomography (CT) scans, a recent study demonstrated that the single test with the highest radiation burden, accounting for 22 percent of cumulative effective dose from medical sources, is myocardial perfusion imaging (MPI). Volume of MPI increased from less than 3 million procedures in the United States in 1990 to 9.3 million in 2002, and it is now estimated to account for more than 10 percent of the entire cumulative effective dose to the U.S. population from all sources, excluding radiotherapy," according to background information in the article. Few data are available to characterize the total radiation burden received over an extended period by patients undergoing MPI.

Andrew J. Einstein, M.D., Ph.D., of Columbia University Medical Center and New York-Presbyterian Hospital, New York, and colleagues analyzed procedures involving ionizing radiation received by a group of patients who received MPI to evaluate the total numbers of MPI examinations, other tests involving radiation, cumulative effective doses of radiation, and clinical indications for testing and repeat testing. The study included 1,097 patients undergoing MPI during the first 100 days of 2006 (January 1-April 10) at Columbia University Medical Center. The researchers evaluated all preceding medical imaging procedures involving ionizing radiation undergone beginning October 1988, and all subsequent procedures through June 2008, at the center.

Patients underwent a median (midpoint) of 15 procedures involving radiation exposure, of which 4 were high-dose procedures, defined as an effective dose of at least 3 mSv (millisievert; a measure of radiation dose), the equivalent of 1 year's natural background radiation. A total of 200 patients (18.2 percent) had at least 3 MPIs and 4.9 percent had at least 5 MPI examinations.

The researchers found that the median cumulative estimated effective dose from MPI alone was 28.9 mSv, and for all medical testing, was 64.0 mSv. A total of 71 patients (6.5 percent) received cumulative doses of more than 100 mSv due to MPI alone, and 31.4 percent of patients received more than 100 mSv from all medical sources, including 120 patients (10.9 percent) who received cumulative dose of more than 200 mSv.

The primary reason for testing was chest pain, breathing difficulty, or both in 66.8 percent of examinations. More than 80 percent of initial and 90 percent of repeat MPI examinations were performed in patients with known cardiac disease or symptoms consistent with it. Of 1,097 patients undergoing index MPI, 38.6 percent underwent additional MPI studies. For this group of patients undergoing multiple MPIs, the median cumulative estimated effective dose was 121 mSv.

Patients undergoing multiple MPI examinations were significantly more likely to be older and male. Men and white patients had higher cumulative estimated effective doses.

"Our study reveals very high cumulative estimated effective doses to many patients undergoing MPI, and especially to patients undergoing repeat MPI testing. More than 30 percent of patients received a cumulative estimated effective dose of more than 100 mSv, a level at which there is little controversy over the potential for increased cancer risks," the authors write. "Efforts are needed to decrease this high cumulative dose and its potential attendant risks."

They add that "although the high cumulative doses observed are certainly a matter of concern and an important target for improvement, these doses should not be viewed in isolation but rather within the clinical context where radiation risk for a specific patient is balanced against potential benefits."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Common for patients to undergo multiple cardiac imaging tests, with high cumulative radiation dose." ScienceDaily. ScienceDaily, 15 November 2010. <www.sciencedaily.com/releases/2010/11/101115091850.htm>.
JAMA and Archives Journals. (2010, November 15). Common for patients to undergo multiple cardiac imaging tests, with high cumulative radiation dose. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2010/11/101115091850.htm
JAMA and Archives Journals. "Common for patients to undergo multiple cardiac imaging tests, with high cumulative radiation dose." ScienceDaily. www.sciencedaily.com/releases/2010/11/101115091850.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins