Featured Research

from universities, journals, and other organizations

Brittle bones and heart disease go hand in hand

Date:
December 3, 2010
Source:
The Research Council of Norway
Summary:
Norwegian studies indicate that people with osteoporosis have a greater risk of developing cardiovascular disease, and vice versa. Now researchers believe they have found a biological system that may influence both disease processes.

Norwegian studies indicate that people with osteoporosis have a greater risk of developing cardiovascular disease, and vice versa. Now researchers believe they have found a biological system that may influence both disease processes.

Related Articles


Today over 400,000 Norwegians have some form of cardiovascular disease, according to figures from the Norwegian Society of Public Health. These diseases are the most frequent cause of death of both men and women in Norway.

Osteoporosis is another common, widespread disease. One-half of all Norwegian women and one-fourth of all Norwegian men will experience at least one bone fracture after they have turned 50.

Now it appears that in some cases the same mechanism is at work in both disease processes, making us more vulnerable to osteoporosis and heart attack and stroke.

Greater risk of stroke

Osteoporosis is a disease in which a reduction of the mineral content of the bones results in low bone density. In 2001, Professor Lone Jørgensen and her colleagues at the University of Tromsø published a study showing that women who had suffered a stroke had much lower bone density than other women of the same age.

"This finding piqued our interest in looking for potential connections between osteoporosis and atherosclerosis ('hardening of the arteries'). Atherosclerosis is a disease in which fatty material, calcium and connective tissue collect along the walls of arteries. It is a common cause of stroke and other cardiovascular diseases," Dr Jørgensen explains.

The researchers carried out a project to study some of the possible connections between osteoporosis and the risk of developing cardiovascular disease using data from about 6 000 men and women who participated in a special survey in 1994-1995 and 2001-2002, which was part of the comprehensive Tromsø study of cardiovascular diseases. The project ran from 2006 to 2009, and was funded by the Research Council's allocations earmarked for women's health research.

A possible connection found

"It appears there is a connection between low bone density and the type of atherosclerotic changes that are rich in connective tissue and calcium. Women who exhibit these changes also have a higher risk of bone fracture," Dr Jørgensen says. In many cases, a person may develop osteoporosis and suffer a heart attack for completely different reasons. But there may be a causal relationship between the diseases. Data from several research groups now indicate that a biological system involving osteoprotegerin (OPG), among other things, may be a common denominator.

"We have found that bone loss is linked to a high level of OPG in post-menopausal women. In addition, we see that a high level of OPG also predicts the development of atherosclerosis in women," she continues.

Prevention

The researchers want to learn more about the role played by the system of which OPG is a part.

"Our contribution will be to find out as much as possible about the connections between these One-half of all Norwegian women and one-fourth of all Norwegian men will experience at least one bone fracture after they have turned 50.diseases in the population in general and the factors that influence them. We hope that our findings will help to develop methods of preventing these serious diseases," Dr Jørgensen concludes.


Story Source:

The above story is based on materials provided by The Research Council of Norway. The original article was written by Elin Fugelsnes/Else Lie; translation by Connie Stultz/Victoria Coleman. Note: Materials may be edited for content and length.


Cite This Page:

The Research Council of Norway. "Brittle bones and heart disease go hand in hand." ScienceDaily. ScienceDaily, 3 December 2010. <www.sciencedaily.com/releases/2010/12/101201095818.htm>.
The Research Council of Norway. (2010, December 3). Brittle bones and heart disease go hand in hand. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2010/12/101201095818.htm
The Research Council of Norway. "Brittle bones and heart disease go hand in hand." ScienceDaily. www.sciencedaily.com/releases/2010/12/101201095818.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) — The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) — Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) — Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) — Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins