Featured Research

from universities, journals, and other organizations

Blood protein in lung cancer could improve diagnosis and treatment

Date:
March 3, 2011
Source:
American Chemical Society
Summary:
Scientists are reporting discovery of a protein in the blood of lung cancer patients that could be used in a test for the disease -- difficult to diagnose in its earliest and most treatable stages -- and to develop drugs that stop lung cancer from spreading.

Scientists are reporting discovery of a protein in the blood of lung cancer patients that could be used in a test for the disease -- difficult to diagnose in its earliest and most treatable stages -- and to develop drugs that stop lung cancer from spreading. Their study appears in ACS's Journal of Proteome Research.

In the report, Je-Yoel Cho and colleagues note that lung cancer is the leading cause of cancer deaths worldwide. Lung cancer is so deadly because of its tendency to spread -- or metastasize -- to distant sites in the body, such as the liver or the brain. Early detection could improve survival rates, but it is very difficult to detect lung cancer at early stages with today's technology. To find a better diagnostic tool, the researchers studied the proteins in the blood of lung cancer patients in search of red flags that could signal the disease's presence. They focused on adenocarcinoma, which accounts for 1 in 3 cases and is the most rapidly increasing form of lung cancer in women.

Cho and colleagues found elevated levels of a protein called serum amyloid A (SAA) in the blood and lung tissue of lung adenocarcinoma patients, compared to healthy people. Their work showed that high amounts of SAA were unique to lung cancers (compared with other lung diseases or other cancers) and that the protein was involved in metastasis of cancer cells from the original tumor site. The researchers say that the protein could be used as a diagnostic marker for lung cancer and as a target for developing drugs that stop metastasis.

The authors acknowledge funding from the Korean Ministry of Education, Science and Technology; the Small and Medium Business Administration; and the Ministry of Knowledge Economy.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hye-Jin Sung, Jung-Mo Ahn, Yeon-Hee Yoon, Tai-Youn Rhim, Choon-Sik Park, Jae-Yong Park, Soo-Youn Lee, Jong-Won Kim, Je-Yoel Cho. Identification and Validation of SAA as a Potential Lung Cancer Biomarker and its Involvement in Metastatic Pathogenesis of Lung Cancer. Journal of Proteome Research, 2011; 110125110723047 DOI: 10.1021/pr101154j

Cite This Page:

American Chemical Society. "Blood protein in lung cancer could improve diagnosis and treatment." ScienceDaily. ScienceDaily, 3 March 2011. <www.sciencedaily.com/releases/2011/03/110302121706.htm>.
American Chemical Society. (2011, March 3). Blood protein in lung cancer could improve diagnosis and treatment. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2011/03/110302121706.htm
American Chemical Society. "Blood protein in lung cancer could improve diagnosis and treatment." ScienceDaily. www.sciencedaily.com/releases/2011/03/110302121706.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com
Michigan Man Sees Thanks to 'bionic Eye'

Michigan Man Sees Thanks to 'bionic Eye'

AP (Apr. 23, 2014) A legally blind Michigan man is 'seeing something new every day' thanks to a high-tech retinal implant procedure. He's one of the first in the country to receive a 'bionic eye' since the federal government approved the surgery. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins