Featured Research

from universities, journals, and other organizations

Low testosterone linked to varicoceles

Date:
June 16, 2011
Source:
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Summary:
As many as 15 percent of men have varicoceles, masses of enlarged and dilated veins in the testicles. There is new evidence that varicoceles, long known to be a cause of male infertility, interfere with the production of testosterone -- a crucial hormone to maintaining men's health.

As many as 15 percent of men have varicoceles, masses of enlarged and dilated veins in the testicles. There is new evidence that varicoceles, long known to be a cause of male infertility, interfere with the production of testosterone -- a crucial hormone to maintaining men's health.

Related Articles


There is good news too: Microsurgery can increase testosterone levels in these men. Results of new research by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center are in a recent edition of BJU International.

"Varicoceles are a much more serious problem than previously thought. Low testosterone causes significant health problems in men. Besides causing low energy, decreased muscle strength and sexual problems, it is a major risk factor for osteopenia/osteoporosis and can also cause changes in cognitive and psychological function, in particular, depression," says Dr. Marc Goldstein, who initiated and led the study. He is the Matthew P. Hardy Distinguished Professor of Reproductive Medicine and a professor of urology at Weill Cornell Medical College and surgeon-in-chief of male reproductive medicine and surgery at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. He is also senior scientist with the Population Council's Center for Biomedical Research, located on the campus of Rockefeller University.

Varicoceles usually first appear during or shortly after puberty, explains Dr. Goldstein. "The common wisdom has been to leave them alone unless they are causing pain or infertility. But, as a result of our study, I recommend that teenagers and men with serious varicoceles be referred to a male reproductive urologist experienced in microsurgical varicocelectomy. It is much easier to prevent future fertility problems and low testosterone than wait until the damage has already occurred."

Adult men with a varicocele and low testosterone should also consider microsurgery sooner rather than later, says Dr. Goldstein. "The microsurgery techniques available today (and developed, in large part, at NewYork-Presbyterian/Weill Cornell) have a very low complication and failure rate compared with the more invasive techniques used in the past. Microsurgery is a good choice for men with low testosterone as there are no oral medications to increase testosterone. And although testosterone shots, pellets and gels are effective, they are not tolerable or appropriate for many patients, such as men trying to conceive, and are certainly less convenient than making your own testosterone."

In the current study, Dr. Goldstein and his colleagues measured the preoperative testosterone levels of 325 men with varicoceles and in 510 men without varicoceles. They found that men at every age with varicoceles had significantly lower testosterone levels (416 vs. 469 ng/dL) than the comparison group. After undergoing microsurgical varicocelectomy, testosterone levels significantly increased in 70 percent of the patients, with a mean increase of 178 ng/dL.

"This research indicates that varicocele surgery, at the least, prevents further deterioration of testosterone production," says Dr. Cigdem Tanrikut, one of the authors of the study. Dr. Tanrikut did a fellowship in male reproductive medicine and microsurgery under Dr. Goldstein. She is currently assistant professor of surgery at Harvard Medical School, a urologist at Massachusetts General Hospital and an adjunct assistant professor of urology and reproductive medicine at Weill Cornell Medical College.

Besides Drs. Goldstein and Tanrikut, contributing authors are Drs. James S. Rosoff and Richard K. Lee from NewYork-Presbyterian/Weill Cornell. Dr. John P. Mulhall and Christian J. Nelson are at Memorial Sloan-Kettering Cancer Center. Dr. Mulhall has a joint appointment at Weill Cornell Medical College.


Story Source:

The above story is based on materials provided by New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cigdem Tanrikut, Marc Goldstein, James S. Rosoff, Richard K. Lee, Christian J. Nelson, John P. Mulhall. Varicocele as a risk factor for androgen deficiency and effect of repair. BJU International, 2011; DOI: 10.1111/j.1464-410X.2010.10030.x

Cite This Page:

New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College. "Low testosterone linked to varicoceles." ScienceDaily. ScienceDaily, 16 June 2011. <www.sciencedaily.com/releases/2011/06/110616142726.htm>.
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College. (2011, June 16). Low testosterone linked to varicoceles. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2011/06/110616142726.htm
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College. "Low testosterone linked to varicoceles." ScienceDaily. www.sciencedaily.com/releases/2011/06/110616142726.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins