Featured Research

from universities, journals, and other organizations

Non-cocaine, topical anesthetics can kill pain when repairing skin wounds

Date:
July 27, 2011
Source:
Wiley-Blackwell
Summary:
While some pain killers need to be injected into the damaged tissue in order to work, topical anesthetics only need to be spread on the surface. The earliest examples of "topical" anesthetics contained cocaine, but now a new systematic review has shown that newer agents that don't contain cocaine can effectively treat pain caused by torn skin. This makes these pain killers an attractive choice for doctors who need to sew-up a patient's skin wound.

While some pain killers need to be injected into the damaged tissue in order to work, topical anesthetics only need to be spread on the surface. The earliest examples of "topical" anesthetics contained cocaine, but now a new systematic review has shown that newer agents that don't contain cocaine can effectively treat pain caused by torn skin. This makes these pain killers an attractive choice for doctors who need to sew-up a patient's skin wound.

This finding was reached after a team of Cochrane researchers analyzed data from 32 randomized control trials that together involved 3128 patients.

Wiping or placing an anesthetic cream, gel or patch onto damage skin can be easier to perform and less painful to the patient than injecting a pain killer through a needle. The first versions of this form of pain killer used cocaine. That, however, makes the pain killer difficult to use in practice, because there are concerns over possible harms and in many countries cocaine use is tightly controlled. Consequently the pharmaceutical industry has produced a range of non-cocaine topical anesthetics.

"The research clearly showed that cocaine-free topical anesthetics can substantially reduce pain without triggering serious side effects," says the study's lead researcher Anthony Eidelman, who works at the Olathe Medical Center in Kansas. He adds that because the trials varied widely in the ways that they were performed and the ways that pain was measured, his team was unable to draw any more detailed conclusions.

"We need to encourage people to do more research using non-cocaine topical anesthetics, but this time perform the research in ways that are sufficiently rigorous. These agents look promising at the moment, but it would be great to confirm their value with high-quality research," says Eidelman.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Anthony Eidelman, Jocelyn M Weiss, Cristy L Baldwin, Ikay K Enu, Ewan D McNicol, Daniel B Carr. Topical anaesthetics for repair of dermal laceration. , DOI: 10.1002/14651858.CD005364.pub2

Cite This Page:

Wiley-Blackwell. "Non-cocaine, topical anesthetics can kill pain when repairing skin wounds." ScienceDaily. ScienceDaily, 27 July 2011. <www.sciencedaily.com/releases/2011/07/110727083446.htm>.
Wiley-Blackwell. (2011, July 27). Non-cocaine, topical anesthetics can kill pain when repairing skin wounds. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2011/07/110727083446.htm
Wiley-Blackwell. "Non-cocaine, topical anesthetics can kill pain when repairing skin wounds." ScienceDaily. www.sciencedaily.com/releases/2011/07/110727083446.htm (accessed April 19, 2014).

Share This



More Mind & Brain News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Study On Artists' Brain Shows They're 'Structurally Unique'

Study On Artists' Brain Shows They're 'Structurally Unique'

Newsy (Apr. 17, 2014) The brains of artists aren't really left-brain or right-brain, but rather have extra neural matter in visual and motor control areas. Video provided by Newsy
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Are School Dress Codes Too Strict?

Are School Dress Codes Too Strict?

AP (Apr. 16, 2014) Pushing the limits on style and self-expression is a rite of passage for teens and even younger kids. How far should schools go with their dress codes? The courts have sided with schools in an era when school safety is paramount. (April 16) Video provided by AP
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins