Featured Research

from universities, journals, and other organizations

Success in treatment for kidney transplant patients

Date:
August 3, 2011
Source:
Medical University of Vienna
Summary:
There is now a new alternative to immunosuppressive treatment after kidney transplants which comes without the usual severe side effects.

There is now a new alternative to immunosuppressive treatment after kidney transplants which comes without the usual severe side effects. The Medical University was significantly involved in the clinical development of the active ingredient Belatacept and a suitable preparation has now been given EU-wide authorisation.

"This could fundamentally revolutionise kidney transplantation and its treatment," says Ferdinand Mühlbacher, director of the University Department of Surgery and together with the immunologist Thomas Wekerle, head of the Viennese study centre. Instead of nine years, a transplanted kidney supported with Belatacept can last 13 years according to conservative estimations. Mühlbacher is somewhat more optimistic. "I estimate 15 to 17 years." Nine out of 22 patients are still involved in the Vienna scientist's long-term study. They are being treated with the substance ten years after a transplant. "Their kidney functions are excellent," says Mühlbacher.

The advantage of the co-stimulation blocker Belatacept is easily explained as contrary to the usual immunosuppressants, the calcineurin inhibitors such as ciclosporin for example, Belatacept does not have any side effects. For almost 30 years calcineurin inhibitors have been used for the life-long suppression of the immune system's undesired reactions following organ transplants. The possible side effects such as high blood pressure, diabetes or lipid metabolism disorders used to have to be considered. Mühlbacher says, "However we now have a substance which is as effective, which is not toxic, which does not have any side effects, and which ensures better organ function."

With transplants there is still the fundamentally increased risk of cancer which according to Mühlbacher is as high with the active ingredient Betalacept as with the calcineurin inhibitors. Around 420 transplants are performed at the MedUni Vienna each year and 180 of these involve kidneys. "We shall of course not now change all of our patients to the new medicine, however we shall of course consider this for new patients," says Mühlbacher.


Story Source:

The above story is based on materials provided by Medical University of Vienna. Note: Materials may be edited for content and length.


Cite This Page:

Medical University of Vienna. "Success in treatment for kidney transplant patients." ScienceDaily. ScienceDaily, 3 August 2011. <www.sciencedaily.com/releases/2011/08/110802112834.htm>.
Medical University of Vienna. (2011, August 3). Success in treatment for kidney transplant patients. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2011/08/110802112834.htm
Medical University of Vienna. "Success in treatment for kidney transplant patients." ScienceDaily. www.sciencedaily.com/releases/2011/08/110802112834.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) — Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) — Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) — A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins