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Estrogen may prevent younger menopausal women from strokes, study suggests

Date:
October 17, 2011
Source:
Mayo Clinic
Summary:
Estrogen may prevent strokes in premature or early menopausal women, researchers have found in a new study. Their findings challenge the conventional wisdom that estrogen is a risk factor for stroke at all ages.

Estrogen may prevent strokes in premature or early menopausal women, Mayo Clinic researchers say. Their findings challenge the conventional wisdom that estrogen is a risk factor for stroke at all ages.

The study was published in the journal Menopause.

Researchers combined the results from a recent Mayo Clinic study with six other studies from across the world and found that estrogen is protective for stroke before age 50. That is roughly the average age when women go through menopause.

"We were very surprised because these results were unexpected," says study author Walter Rocca, M.D., an epidemiologist and neurologist at Mayo Clinic. "The old idea that estrogen is always a problem in the brain has to be corrected." Estrogen can be a problem in older women, he explains, but in younger women, estrogen may be important to protect the brain from strokes.

The study has implications for women who experience premature (before age 40) or early menopause (before age 45) from natural causes or from ovary removal. Women in these groups should consider taking estrogen up to approximately age 50 to prevent stroke, Dr. Rocca says.

Ischemic stroke occurs as a result of an obstruction within a blood vessel supplying blood to the brain. According to the American Stroke Association, these types of strokes account for 87 percent of all stroke cases.

Co-authors of the study include: Brandon Grossardt, M.S.; Virginia Miller, Ph.D.; Lynne Shuster, M.D.; Robert Brown, Jr., M.D.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Journal Reference:

  1. Walter A. Rocca, Brandon R. Grossardt, Virginia M. Miller, Lynne T. Shuster, Robert D. Brown. Premature menopause or early menopause and risk of ischemic stroke. Menopause, 2011; DOI: 10.1097/gme.0b013e31822a9937

Cite This Page:

Mayo Clinic. "Estrogen may prevent younger menopausal women from strokes, study suggests." ScienceDaily. ScienceDaily, 17 October 2011. <www.sciencedaily.com/releases/2011/10/111012144142.htm>.
Mayo Clinic. (2011, October 17). Estrogen may prevent younger menopausal women from strokes, study suggests. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2011/10/111012144142.htm
Mayo Clinic. "Estrogen may prevent younger menopausal women from strokes, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/10/111012144142.htm (accessed September 1, 2014).

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