Featured Research

from universities, journals, and other organizations

New test can better predict successful IVF embryos, scientists say

Date:
February 29, 2012
Source:
University College Dublin
Summary:
Scientists have discovered a new way of measuring the potential success rate of an embryo before it is transferred back into the womb during in vitro fertilization (IVF). According to the findings, the fluid within a woman's ovaries that surrounds the egg or oocyte holds metabolic information that can improve predictions on which embryo is more likely to lead to pregnancy.

Scientists at University College Dublin have discovered a new way of measuring the potential success rate of an embryo before it is transferred back into the womb during in vitro fertilisation (IVF).

Related Articles


According to the findings published online in the journal Fertility and Sterility, the fluid within a woman's ovaries that surrounds the egg or oocyte holds metabolic information that can improve predictions on which embryo is more likely to lead to pregnancy.

"We analysed samples of the follicular fluid surrounding the immature ovum or egg before it was retrieved for IVF," says Dr Lorraine Brennan, UCD Conway Institute, University College Dublin, Ireland.

"We identified clear metabolic differences between the follicular fluids from women who successfully achieved pregnancy as a result of IVF to the fluids from the women who did not."

"Before the test can be regularised for use during IVF, our results need to be validated across a larger cohort of women undergoing treatment, and we are hopeful that the results obtained from larger samples will support our initial findings," says Dr Brennan.

Today, approximately 32% of IVF cycles result in pregnancy, so the standard procedure involves the transfer of multiple embryos back into the womb to increase the potential success rate.

But when more than one embryo is transferred back, there is an increased chance of multiple births like twins and triplets. There are increased health risks associated with multiple pregnancies for both mother and infants including an increased risk of miscarriages and preterm labour, leading to premature infants with admission to neonatal intensive care.

"In more recent years there has been an increase in the number of single embryo transfer (SET) as an effective way of reducing potential multiple births, but the widespread acceptance of SET is limited because there is no fully accurate method of embryo assessment and selection for transfer during IVF cycles."


Story Source:

The above story is based on materials provided by University College Dublin. Note: Materials may be edited for content and length.


Journal Reference:

  1. Martina Wallace, Evelyn Cottell, Michael J. Gibney, Fionnuala M. McAuliffe, Mary Wingfield, Lorraine Brennan. An investigation into the relationship between the metabolic profile of follicular fluid, oocyte developmental potential, and implantation outcome. Fertility and Sterility, 2012; DOI: 10.1016/j.fertnstert.2012.01.122

Cite This Page:

University College Dublin. "New test can better predict successful IVF embryos, scientists say." ScienceDaily. ScienceDaily, 29 February 2012. <www.sciencedaily.com/releases/2012/02/120229105029.htm>.
University College Dublin. (2012, February 29). New test can better predict successful IVF embryos, scientists say. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2012/02/120229105029.htm
University College Dublin. "New test can better predict successful IVF embryos, scientists say." ScienceDaily. www.sciencedaily.com/releases/2012/02/120229105029.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New FDA-Approved Diabetes Medicine Might Save Drugmaker

New FDA-Approved Diabetes Medicine Might Save Drugmaker

Newsy (Feb. 26, 2015) The U.S. Food and Drug Administration approved new diabetes drug Toujeo on Wednesday, a move that might save French drugmaker Sanofi&apos;s profits. Video provided by Newsy
Powered by NewsLook.com
The Best Foods to Battle Stress

The Best Foods to Battle Stress

Buzz60 (Feb. 26, 2015) If you&apos;re dealing with anxiety, there are a few foods that can help. Krystin Goodwin (@krystingoodwin) has the best foods to tame stress. Video provided by Buzz60
Powered by NewsLook.com
The 5 Best Tips to Look Younger Now

The 5 Best Tips to Look Younger Now

Buzz60 (Feb. 26, 2015) Life happens, and we all get older, but forget the pricey anti-aging products and plastic surgery. You can tweak your habits to turn back the hands of time. Krystin Goodwin (@krystingoodwin) has a few simple tips to help you look and feel younger. Video provided by Buzz60
Powered by NewsLook.com
Sleeping Too Much Or Too Little Might Increase Stroke Risk

Sleeping Too Much Or Too Little Might Increase Stroke Risk

Newsy (Feb. 26, 2015) People who sleep more than eight hours per night are 45 percent more likely to have a stroke, according to a University of Cambridge study. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins