Featured Research

from universities, journals, and other organizations

Single dose radiation at time of surgery helps women with early stage breast cancer forego 6-7 week radiation regimen

Date:
July 5, 2012
Source:
NewYork-Presbyterian Hospital/Columbia University Medical Center and NewYork-Presbyterian Hospital/W
Summary:
INTRABEAM radiotherapy is an innovative radiation treatment delivered in a single dose at the time of surgery.

NewYork-Presbyterian Hospital/Weill Cornell Medical Center is the first and only hospital in the five boroughs of New York City to offer women with early stage breast cancer INTRABEAM radiotherapy, an innovative radiation treatment delivered in a single dose at the time of surgery.

Women with early stage breast cancer often have breast-conserving surgery, otherwise known as a lumpectomy, to remove a cancerous tumor. Lumpectomy is followed by a regimen of daily doses of radiation therapy to the entire breast, generally lasting six to seven consecutive weeks.

"INTRABEAM Radiotherapy may be an effective alternative to a six to seven week regimen following surgery for select patients because it allows us to precisely target any remaining cancer cells right inside the tumor bed, where the tumor is most likely to recur," says Dr. Mary Katherine Hayes, clinical director of Radiation Oncology at NewYork-Presbyterian Hospital/Weill Cornell Medical Center and associate professor of Clinical Radiology and Radiation Oncology at Weill Cornell Medical College.

Immediately following removal of the tumor, while the patient is still on the operating table, the INTRABEAM applicator's small, cylindrical tip is placed inside the tumor cavity to deliver a superficial dose of radiation for 20-30 minutes, while limiting exposure to healthy surrounding tissue and organs. After the applicator is removed, the surgical incision is closed.

"Our ability to use this radiation technique in such a timely manner may add to its effectiveness since the area in need of treatment can be directly visualized at the moment the tumor is removed," say Dr. Alexander J. Swistel, attending breast surgeon at the Iris Cantor Women's Health Center at NewYork-Presbyterian/Weill Cornell Medical Center and associate professor of clinical surgery at Weill Cornell Medical College.

This alternative to conventional full-breast radiation therapy is in step with the hospital's longstanding practice of tailoring partial breast cancer treatments to a growing number of patients with a small, early stage tumor. Eliminating an additional 6-7 weeks of radiation therapy is particularly convenient for patients who do not live in close proximity to a hospital or an established radiation therapy facility.

A 10-year randomized phase 3 clinical trial of intraoperative therapy for breast cancer found that for selected patients, single dose radiotherapy delivered at the time of surgery yielded the same results as conventional full breast radiation delivered over several weeks. The TARGIT-A Trial, published in The Lancet in July 2010, studied only the INTRABEAM system and was the largest randomized clinical trial conducted in this field, more than two thousand women in multiple countries were enrolled.

While INTRABEAM is limited to a select group of patients with a very small tumor, if tissue samples removed during surgery prove more aggressive than preliminary tests revealed, the patient will still be able to undergo conventional full-breast radiation. However, the patient would not need to undergo the final five-day phase of conventional treatment, known as boost therapy, which targets the tumor bed with external radiation.


Story Source:

The above story is based on materials provided by NewYork-Presbyterian Hospital/Columbia University Medical Center and NewYork-Presbyterian Hospital/W. Note: Materials may be edited for content and length.


Cite This Page:

NewYork-Presbyterian Hospital/Columbia University Medical Center and NewYork-Presbyterian Hospital/W. "Single dose radiation at time of surgery helps women with early stage breast cancer forego 6-7 week radiation regimen." ScienceDaily. ScienceDaily, 5 July 2012. <www.sciencedaily.com/releases/2012/07/120705171944.htm>.
NewYork-Presbyterian Hospital/Columbia University Medical Center and NewYork-Presbyterian Hospital/W. (2012, July 5). Single dose radiation at time of surgery helps women with early stage breast cancer forego 6-7 week radiation regimen. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2012/07/120705171944.htm
NewYork-Presbyterian Hospital/Columbia University Medical Center and NewYork-Presbyterian Hospital/W. "Single dose radiation at time of surgery helps women with early stage breast cancer forego 6-7 week radiation regimen." ScienceDaily. www.sciencedaily.com/releases/2012/07/120705171944.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins