Featured Research

from universities, journals, and other organizations

Brain scans don't lie about age

Date:
August 16, 2012
Source:
Cell Press
Summary:
It isn't uncommon for people to pass for ages much older or younger than their years, but researchers have now found that this feature doesn't apply to our brains. The findings show that sophisticated brain scans can be used to accurately predict age, give or take a year.

The "developmental clock" shows increases and decreases in brain's cortical surface, as well as the dynamic cascade of many other brain measures, all changing with increasing age (from age 3-20).
Credit: University of California San Diego of Medicine

It isn't uncommon for people to pass for ages much older or younger than their years, but researchers have now found that this feature doesn't apply to our brains. The findings reported online on August 16 in Current Biology, a Cell Press publication, show that sophisticated brain scans can be used to accurately predict age, give or take a year.

It's a "carnival trick" that may have deeper implications for both brain science and medicine.

"We have uncovered a 'developmental clock' of sorts within the brain -- a biological signature of maturation that captures age differences quite well, regardless of other kinds of differences that exist across individuals," says Timothy Brown of the University of California, San Diego School of Medicine.

Together with UCSD's Anders Dale and Terry Jernigan and researchers from nine other universities, Brown used structural magnetic resonance imaging (MRI) to scan the brains of 885 people ranging in age from 3 to 20. Those brain scans were used to identify 231 biomarkers of brain anatomy that, when combined, could assess an individual's age with more than 92 percent accuracy. That's beyond what's been possible with any other biological measure, the researchers say.

While others had looked at some of the same brain biomarkers in the past one by one, the key was finding a way to combine them to capture the multidimensional nature of brain anatomy and characteristic patterns of developmental change with age. Brown says that they are excited to further explore the new approach and its potential for use in the clinic.

"The fact that we found a collection of brain measures that so accurately captures a person's chronological age means that brain development, or at least certain anatomical aspects of it, is more tightly controlled than we knew previously," Brown says. "The regularity in this maturity metric among typically developing children suggests that it might be sensitive to detecting abnormality as well."

It's not yet clear how these anatomical changes in the brain will relate to maturity in terms of human behavior, which we all know isn't necessarily reflected by our chronological age.

"The anatomy and physiology of these dynamic, interacting neural systems, which we can probe in different ways with MRI scans, have to account for the changes we all observe in human psychological development," Brown says. "We're still figuring out exactly how."


Story Source:

The above story is based on materials provided by Cell Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. TimothyT. Brown, JoshuaM. Kuperman, Yoonho Chung, Matthew Erhart, Connor McCabe, DonaldJ. Hagler, VijayK. Venkatraman, Natacha Akshoomoff, DavidG. Amaral, CinnamonS. Bloss, B.J. Casey, Linda Chang, ThomasM. Ernst, JeanA. Frazier, JeffreyR. Gruen, WalterE. Kaufmann, Tal Kenet, DavidN. Kennedy, SarahS. Murray, ElizabethR. Sowell, TerryL. Jernigan, AndersM. Dale. Neuroanatomical Assessment of Biological Maturity. Current Biology, 2012; DOI: 10.1016/j.cub.2012.07.002

Cite This Page:

Cell Press. "Brain scans don't lie about age." ScienceDaily. ScienceDaily, 16 August 2012. <www.sciencedaily.com/releases/2012/08/120816121954.htm>.
Cell Press. (2012, August 16). Brain scans don't lie about age. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2012/08/120816121954.htm
Cell Press. "Brain scans don't lie about age." ScienceDaily. www.sciencedaily.com/releases/2012/08/120816121954.htm (accessed July 24, 2014).

Share This




More Mind & Brain News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com
Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

More Coverage


Multi-Dimensional Brain Measurements Can Assess Child’s Age

Aug. 16, 2012 Scientists have developed a multidimensional set of brain measurements that, when taken together, can accurately assess a child’s age with 92 percent ... read more
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins