Featured Research

from universities, journals, and other organizations

People who get kidney stones more likely to develop kidney failure

Date:
September 6, 2012
Source:
University of Alberta Faculty of Medicine & Dentistry
Summary:
People who have had kidney stones are twice as likely to need dialysis or a kidney transplant later in life, demonstrates recent findings.

People who have had kidney stones are twice as likely to need dialysis or a kidney transplant later in life, demonstrates recently published findings by medical researchers at the University of Alberta. Their article was recently published in the British Medical Journal.

Faculty of Medicine & Dentistry researchers Todd Alexander and Marcello Tonelli tracked data of more than three million Albertans over an 11-year period from 1997 to 2009. They discovered those with a history of kidney stones were twice as likely to have serious kidney problems later in life when compared to people who had never suffered from kidney stones. And women under the age of 50 who had a history of kidney stones were four times as likely to later develop kidney failure. Although the actual number of those who developed kidney failure was small, the link to having a history of kidney stones was noteworthy.

"I think what these results tell me, is that we should be screening those with a history of kidney stones for risk factors for the development of kidney disease," says Alexander, the study's first author and a practising pediatric nephrologist.

"I am not surprised by these findings because when you are passing a stone through a kidney, there is definitely the potential for permanent damage."

Based on their findings, between five and seven per cent of Albertans will develop a kidney stone in their lifetime, says Alexander. The data is more alarming in the United States where 10 to 11 per cent of the population develops kidney stones. Half of those who get kidney stones will have a reoccurrence -- anywhere from one to several more episodes.

"It's important to note that the vast majority of people with kidney stones won't develop permanent kidney damage," adds Tonelli. "But a few will, and that's why it's important for people with stones to get proper follow-up care -- to reduce their risk of another stone, and to detect kidney damage if it has occurred."

People could try to decrease the likelihood of the development of kidney stones by decreasing their sodium intake, drinking more water and, if needed, taking certain medication. It has been previously observed that those who develop kidney stones have kidneys that don't function at optimal levels, which is a factor in the whole issue.

Alexander is a researcher in the Department of Physiology and the Department of Pediatrics, while Tonelli holds a Canada Research Chair in the Department of Medicine's Division of Nephrology.

The primary funders of the research were: The Kidney Foundation of Canada, Alberta Innovates -- Health Solutions, the University Hospital Foundation, and the KRESCENT program (a training and support program for kidney research scientists).


Story Source:

The above story is based on materials provided by University of Alberta Faculty of Medicine & Dentistry. Note: Materials may be edited for content and length.


Journal Reference:

  1. R. T. Alexander, B. R. Hemmelgarn, N. Wiebe, A. Bello, C. Morgan, S. Samuel, S. W. Klarenbach, G. C. Curhan, M. Tonelli. Kidney stones and kidney function loss: a cohort study. BMJ, 2012; 345 (aug29 2): e5287 DOI: 10.1136/bmj.e5287

Cite This Page:

University of Alberta Faculty of Medicine & Dentistry. "People who get kidney stones more likely to develop kidney failure." ScienceDaily. ScienceDaily, 6 September 2012. <www.sciencedaily.com/releases/2012/09/120906131355.htm>.
University of Alberta Faculty of Medicine & Dentistry. (2012, September 6). People who get kidney stones more likely to develop kidney failure. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2012/09/120906131355.htm
University of Alberta Faculty of Medicine & Dentistry. "People who get kidney stones more likely to develop kidney failure." ScienceDaily. www.sciencedaily.com/releases/2012/09/120906131355.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com
Catching More Than Fish: Ugandan Town Crippled by AIDS

Catching More Than Fish: Ugandan Town Crippled by AIDS

AFP (Apr. 22, 2014) The village of Kasensero on the shores of Lake Victoria was where HIV-AIDS was first discovered in Uganda. Its transient population of fishermen and sex workers means the nationwide programme to combat the virus has had little impact. Duration: 02:30 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins