Featured Research

from universities, journals, and other organizations

Disparity in breast cancer between black and white women can be eliminated by regular screening

Date:
September 25, 2012
Source:
Rush University Medical Center
Summary:
Regular mammography screening can help narrow the breast cancer gap between black and white women, according to a retrospective study.

Regular mammography screening can help narrow the breast cancer gap between black and white women, according to a retrospective study published in Breast Cancer Research and Treatment in August.

Related Articles


Earlier studies have shown that black women in Chicago are more than twice as likely to die of breast cancer compared to white women. Black women with breast cancer reach the disease's late stages more often than white women, and their tumors are more likely to be larger and more biologically aggressive.

But according to the study, when women of both races received regular breast cancer screening -- a mammogram within two years of breast cancer diagnosis -- there was no difference in the rate of how many of them presented in the disease's later stages.

The data result from a retrospective study conducted of women diagnosed with breast cancer from January 2001 to December 2006 at Rush University Medical Center and Northwestern Memorial Hospital in Chicago. Data were collected on 1,642 subjects, including 980 who were regularly screened and 662 who were irregularly screened.

"This study reinforces the fact that racial gaps in breast cancer outcomes can be improved," said lead author Dr. Paula Grabler, an assistant professor of radiology at Northwestern University Feinberg School of Medicine and a radiologist at Northwestern Memorial Hospital. "One solution within reach is simple access to routine and regular mammography screening."

One notable finding was that women screened regularly, regardless of race, were more likely to have hormone receptor-positive breast cancers than those who did not receive regular screenings. Breast cancers that are hormone receptor-positive contain receptors for the hormones estrogen and progesterone, making them more responsive to hormone therapy such as tamoxifen or aromatase inhibitors and leads to a better survival. This finding was statistically significant in black women, suggesting that early detection can blunt the development of negative prognostic biological characteristics in some women.

"This suggests that poor prognostic biological factors such as receptor status and tumor grade, once thought to be innate and immutable, may be significantly ameliorated by regular mammography screening, especially in black women," said Dr. David Ansell, the study's senior author and chief medical officer at Rush University Medical Center. "This is a unique finding that will require further exploration."'

Ansell is also chair of the Metropolitan Chicago Breast Cancer Task Force, which includes more than 100 organizations and more than 200 breast cancer experts. In October 2007, the task force released its first major report, "Improving Quality and Reducing Breast Cancer Mortality in Metropolitan Chicago," with 37 recommendations for addressing racial disparities in breast cancer mortality.

In October 2009, the Task Force announced the creation of the Chicago Breast Cancer Quality Consortium. This became the nation's first federally designated Patient Safety Organization dedicated solely to breast health. With the federal protections provided by this designation, 55 hospitals and the Chicago Department of Public Health signed up in 2009 to join the Chicago Breast Cancer Quality Consortium project and share quality data to identify deficits and implement strategies to improve breast cancer screening and treatment.

Besides Drs. Ansell and Grabler, Danielle Dupuy (Metropolitan Chicago Breast Cancer Taskforce), Jennifer Rai (University of Michigan College of Medicine) and Sean Bernstein (University of Nebraska College of Medicine) are co-authors.


Story Source:

The above story is based on materials provided by Rush University Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Paula Grabler, Danielle Dupuy, Jennifer Rai, Sean Bernstein, David Ansell. Regular screening mammography before the diagnosis of breast cancer reduces black:white breast cancer differences and modifies negative biological prognostic factors. Breast Cancer Research and Treatment, 2012; 135 (2): 549 DOI: 10.1007/s10549-012-2193-3

Cite This Page:

Rush University Medical Center. "Disparity in breast cancer between black and white women can be eliminated by regular screening." ScienceDaily. ScienceDaily, 25 September 2012. <www.sciencedaily.com/releases/2012/09/120925153327.htm>.
Rush University Medical Center. (2012, September 25). Disparity in breast cancer between black and white women can be eliminated by regular screening. ScienceDaily. Retrieved January 29, 2015 from www.sciencedaily.com/releases/2012/09/120925153327.htm
Rush University Medical Center. "Disparity in breast cancer between black and white women can be eliminated by regular screening." ScienceDaily. www.sciencedaily.com/releases/2012/09/120925153327.htm (accessed January 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, January 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Oxfam Calls for Massive Aid for Ebola-Hit West Africa

Oxfam Calls for Massive Aid for Ebola-Hit West Africa

AFP (Jan. 29, 2015) Oxfam International has called for a multi-million dollar post-Ebola "Marshall Plan", with financial support given by wealthy countries, to help Guinea, Sierra Leone and Liberia to recover. Duration: 01:10 Video provided by AFP
Powered by NewsLook.com
Are We Winning The Fight Against Ebola?

Are We Winning The Fight Against Ebola?

Newsy (Jan. 29, 2015) The World Health Organization announced the fight against Ebola has entered its second phase as the number of cases per week has steadily dropped. Video provided by Newsy
Powered by NewsLook.com
Calif. Health Officials Campaign Against E-Cigarettes

Calif. Health Officials Campaign Against E-Cigarettes

Newsy (Jan. 29, 2015) The California Health Department says e-cigarettes are a public health risk for both smokers and those who inhale e-cig smoke secondhand. Video provided by Newsy
Powered by NewsLook.com
Measles Scare Sends 66 Calif. Students Home

Measles Scare Sends 66 Calif. Students Home

AP (Jan. 29, 2015) Officials say 66 students at a Southern California high school have been told to stay home through the end of next week because they may have been exposed to measles and are not vaccinated. (Jan. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins