Featured Research

from universities, journals, and other organizations

Progesterone test can predict viability of pregnancy, study finds

Date:
September 27, 2012
Source:
BMJ-British Medical Journal
Summary:
Measuring progesterone levels in women with pain or bleeding during early pregnancy is a useful way to help discriminate between a viable and a non-viable pregnancy, finds a new study.

Measuring progesterone levels in women with pain or bleeding during early pregnancy is a useful way to help discriminate between a viable and a non-viable pregnancy, finds a study published on bmj.com today.

The results suggest that a low level of progesterone in these women can rule out a viable pregnancy in the vast majority of cases.

Vaginal bleeding or pain occurs in around a third of women in early pregnancy. Doctors use ultrasound to test whether it is a viable pregnancy or a non-viable pregnancy, such as a miscarriage or an ectopic pregnancy, but this can sometimes be inconclusive.

Some studies have suggested that a single progesterone measurement in early pregnancy may be a useful test, but results are conflicting.

So a team of UK and Dutch researchers set out to determine the accuracy with which a single progesterone measurement in early pregnancy can discriminate between a viable and a non-viable pregnancy.

They analysed the results of 26 studies involving 9,436 pregnant women. Seven studies looked at women with pain or bleeding and an inconclusive ultrasound assessment, while 19 studies looked at women with pain or bleeding alone.

Differences in study quality were taken into account to identify and minimise bias.

The results show that a single low progesterone measurement for women in early pregnancy presenting with bleeding or pain can discriminate between a viable and a non-viable pregnancy when an ultrasound investigation proves to be inconclusive.

For women with pain or bleeding who did not have an ultrasound, the progesterone test was less accurate in predicting viability of a pregnancy.

The researchers stress that low progesterone levels may occur in some viable pregnancies and, as such, "the test should be complemented by another test to increase its diagnostic accuracy."

They also suggest that "this test is highly accurate when complemented by ultrasound and could be added to the existing algorithms for the evaluation of women with pain or bleeding in early pregnancy as it can accelerate diagnosis."


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Verhaegen J, Gallos ID, van Mello NM, Abdel-Aziz M, Takwoingi Y, Harb H, Deeks JJ, Mol BWJ. Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: meta-analysis of cohort studies. BMJ, 2012; 345: e6077 DOI: 10.1136/bmj.e6077

Cite This Page:

BMJ-British Medical Journal. "Progesterone test can predict viability of pregnancy, study finds." ScienceDaily. ScienceDaily, 27 September 2012. <www.sciencedaily.com/releases/2012/09/120927185914.htm>.
BMJ-British Medical Journal. (2012, September 27). Progesterone test can predict viability of pregnancy, study finds. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2012/09/120927185914.htm
BMJ-British Medical Journal. "Progesterone test can predict viability of pregnancy, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/09/120927185914.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins