Featured Research

from universities, journals, and other organizations

Breast-feeding reduced risk for ER/PR-negative breast cancer, results find

Date:
October 18, 2012
Source:
American Association for Cancer Research (AACR)
Summary:
Breast-feeding reduced the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to new results.

Breast-feeding reduced the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to results presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held in Anaheim, Calif., Oct. 16-19, 2012.

Related Articles


"We found an increased risk for estrogen receptor- and progesterone receptor- (ER/PR) negative breast cancer in women who do not breast-feed, but in women who have children and breast-feed, there is no increased risk," said Meghan Work, M.P.H., doctoral student in the department of epidemiology at Columbia University's Mailman School of Public Health in New York, N.Y.

Work and colleagues examined the relationship between reproductive risk factors -- such as the number of children a woman delivers, breast-feeding and oral contraceptive use -- and ER/PR-negative breast cancer. ER/PR-negative breast cancer often affects younger women and has a poor prognosis, according to Work.

The researchers used data from three sites of the Breast Cancer Family Registry, which includes women with and without breast cancer from the United States, Canada and Australia. This study included 4,011 women with breast cancer and 2,997 population-based controls.

The results indicated that having three or more children without breast-feeding was associated with an increased risk for ER/PR-negative breast cancer.

"Women who had children but did not breast-feed had about 1.5 times the risk for ER/PR-negative breast cancer when compared with a control population," Work said. "If women breast-fed their children, there was no increased risk for ER/PR-negative cancer."

Further, the researchers found that oral contraceptive use was not associated with ER/PR-negative cancer risk, with the exception of those formulations available before 1975. "These earlier formulations contained higher doses of estrogen and progestin than more recent versions," Work said.

These findings are in line with previous findings that have demonstrated breast-feeding benefit in triple-negative breast cancer. "This is particularly important as breast-feeding is a modifiable factor that can be promoted and supported through health policy," Work said.\


Story Source:

The above story is based on materials provided by American Association for Cancer Research (AACR). Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research (AACR). "Breast-feeding reduced risk for ER/PR-negative breast cancer, results find." ScienceDaily. ScienceDaily, 18 October 2012. <www.sciencedaily.com/releases/2012/10/121018121959.htm>.
American Association for Cancer Research (AACR). (2012, October 18). Breast-feeding reduced risk for ER/PR-negative breast cancer, results find. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2012/10/121018121959.htm
American Association for Cancer Research (AACR). "Breast-feeding reduced risk for ER/PR-negative breast cancer, results find." ScienceDaily. www.sciencedaily.com/releases/2012/10/121018121959.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins