Featured Research

from universities, journals, and other organizations

Breast-feeding reduced risk for ER/PR-negative breast cancer, results find

Date:
October 18, 2012
Source:
American Association for Cancer Research (AACR)
Summary:
Breast-feeding reduced the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to new results.

Breast-feeding reduced the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to results presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held in Anaheim, Calif., Oct. 16-19, 2012.

"We found an increased risk for estrogen receptor- and progesterone receptor- (ER/PR) negative breast cancer in women who do not breast-feed, but in women who have children and breast-feed, there is no increased risk," said Meghan Work, M.P.H., doctoral student in the department of epidemiology at Columbia University's Mailman School of Public Health in New York, N.Y.

Work and colleagues examined the relationship between reproductive risk factors -- such as the number of children a woman delivers, breast-feeding and oral contraceptive use -- and ER/PR-negative breast cancer. ER/PR-negative breast cancer often affects younger women and has a poor prognosis, according to Work.

The researchers used data from three sites of the Breast Cancer Family Registry, which includes women with and without breast cancer from the United States, Canada and Australia. This study included 4,011 women with breast cancer and 2,997 population-based controls.

The results indicated that having three or more children without breast-feeding was associated with an increased risk for ER/PR-negative breast cancer.

"Women who had children but did not breast-feed had about 1.5 times the risk for ER/PR-negative breast cancer when compared with a control population," Work said. "If women breast-fed their children, there was no increased risk for ER/PR-negative cancer."

Further, the researchers found that oral contraceptive use was not associated with ER/PR-negative cancer risk, with the exception of those formulations available before 1975. "These earlier formulations contained higher doses of estrogen and progestin than more recent versions," Work said.

These findings are in line with previous findings that have demonstrated breast-feeding benefit in triple-negative breast cancer. "This is particularly important as breast-feeding is a modifiable factor that can be promoted and supported through health policy," Work said.\


Story Source:

The above story is based on materials provided by American Association for Cancer Research (AACR). Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research (AACR). "Breast-feeding reduced risk for ER/PR-negative breast cancer, results find." ScienceDaily. ScienceDaily, 18 October 2012. <www.sciencedaily.com/releases/2012/10/121018121959.htm>.
American Association for Cancer Research (AACR). (2012, October 18). Breast-feeding reduced risk for ER/PR-negative breast cancer, results find. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2012/10/121018121959.htm
American Association for Cancer Research (AACR). "Breast-feeding reduced risk for ER/PR-negative breast cancer, results find." ScienceDaily. www.sciencedaily.com/releases/2012/10/121018121959.htm (accessed August 2, 2014).

Share This




More Health & Medicine News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins