Featured Research

from universities, journals, and other organizations

High altitude climbers at risk for brain bleeds

Date:
November 28, 2012
Source:
Radiological Society of North America
Summary:
New magnetic resonance imaging research shows that mountain climbers who experience a certain type of high altitude sickness have traces of bleeding in the brain years after the initial incident, according to a new study.

New magnetic resonance imaging (MRI) research shows that mountain climbers who experience a certain type of high altitude sickness have traces of bleeding in the brain years after the initial incident, according to a study presented November 28 at the annual meeting of the Radiological Society of North America (RSNA).

High altitude cerebral edema (HACE) is a severe and often fatal condition that can affect mountain climbers, hikers, skiers and travelers at high altitudes -- typically above 7,000 feet, or 2,300 meters.

HACE results from swelling of brain tissue due to leakage of fluids from the capillaries. Symptoms include headache, loss of coordination and decreasing levels of consciousness.

"HACE is a life-threatening condition," said Michael Knauth, M.D., Ph.D., from the University Medical Center's Department of Neuroradiology in Goettingen, Germany. "It usually happens in a hostile environment where neither help nor proper diagnostic tools are available."

Dr. Knauth and colleagues at the University Hospitals in Goettingen and Heidelberg, Germany, compared brain MRI findings among four groups of mountaineers: climbers with well documented episodes of HACE; climbers with a history of high altitude illness; climbers with a history of severe acute mountain sickness (AMS); and climbers with a history of isolated high altitude pulmonary edema (HAPE), a life-threatening accumulation of fluid in the lungs that occurs at high altitudes. Two neuroradiologists assessed the brain MRI findings without knowing the status of the mountaineers and assigned a score based on the number and location of any microhemorrhages.

"In most cases, these microhemorrhages are so small that they are only visible with a special MRI technique called susceptibility-weighted imaging," Dr. Knauth said. "With this technique, the microhemorrhages are depicted as little black spots."

The MRI results showed brain microhemorrhages almost exclusively in HACE survivors. Of the 10 climbers with a history of HACE, eight had evidence of microhemorrhages on MRI. The other two had uncertain results. Only two of the remaining 26 climbers were positive for microhemorrhages.

"It was previously thought that HACE did not leave any traces in the brains of survivors," Dr. Knauth said. "Our studies show that this is not the case. For several years after, microhemorrhages or microbleeds are visible in the brains of HACE survivors."

Survivors of the most clinically severe cases of HACE had the most prominent evidence of microhemorrhages on MRI. The bleeds were found predominantly in the corpus callosum, the thick band of nerve fibers that connects the right and left halves of the brain, and showed a characteristic distribution different from other vascular diseases like vasculitis, or blood vessel inflammation.

"The distribution of microhemorrhages is a new and sensitive MRI sign of HACE and can be detected years after HACE," Dr. Knauth said. "We will further analyze our clinical and MRI data on patients with acute mountain sickness, which is thought to be a precursor of HACE."

In the meantime, Dr. Knauth does not think HACE survivors need to give up climbing.

"We cannot give such a strong recommendation," he said. "However, mountaineers who have already experienced HACE once should acclimatize to the altitude very slowly."

Coauthors are Kai Kallenberg, M.D., Peter Bartsch, M.D., and Kai Schommer, M.D.


Story Source:

The above story is based on materials provided by Radiological Society of North America. Note: Materials may be edited for content and length.


Cite This Page:

Radiological Society of North America. "High altitude climbers at risk for brain bleeds." ScienceDaily. ScienceDaily, 28 November 2012. <www.sciencedaily.com/releases/2012/11/121128093804.htm>.
Radiological Society of North America. (2012, November 28). High altitude climbers at risk for brain bleeds. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2012/11/121128093804.htm
Radiological Society of North America. "High altitude climbers at risk for brain bleeds." ScienceDaily. www.sciencedaily.com/releases/2012/11/121128093804.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins