Featured Research

from universities, journals, and other organizations

Study prompts rethink of how ovaries develop

Date:
February 11, 2013
Source:
University of Adelaide
Summary:
New research will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility.

New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility.

The study, now published in the journal PLOS ONE, also names a new type of cell that plays a key role in the development of ovaries and ovarian follicles, which are responsible for the production of eggs in women.

The discovery is expected to prompt further studies around the world to better understand how ovaries and ovarian follicles develop in female fetuses. This could be critical to treating or preventing a range of health conditions in later life, including infertility and ovarian cancer.

"For more than a decade, scientists have believed that ovarian follicle cells are derived from the epithelial cells on the surface of the ovary as it develops," says research leader Professor Ray Rodgers, from the University of Adelaide's Robinson Institute.

"Instead, contrary to conventional thinking, we've found a new cell type that is the precursor to both the cells on the surface of the ovary and the follicular cells. We call this the GREL (Gonadal Ridge Epithelial-Like) cell."

Professor Rodgers says this work could lead to new insights into a range of conditions, such as premature ovarian failure, early menopause, polycystic ovarian syndrome (PCOS) and ovarian cancer.

"The role of the ovarian follicle in many of these conditions is very important," he says. "For example, the PCOS ovary is associated with an increased number of growing follicles that at some point just stop working.

"With early menopause, there is a theory that some women may not have had enough egg-producing ovarian follicles at development, so once their reserve of follicles has been used up earlier, menopause sets in.

"Ovarian cancer is a different story -- about 90% of ovarian cancers are of an epithelial type. However, our study has shown us for the first time that when the ovary is first developing, it doesn't have an epithelial layer. Why this is, we're not sure yet."


Story Source:

The above story is based on materials provided by University of Adelaide. Note: Materials may be edited for content and length.


Journal Reference:

  1. Katja Hummitzsch, Helen F. Irving-Rodgers, Nicholas Hatzirodos, Wendy Bonner, Laetitia Sabatier, Dieter P. Reinhardt, Yoshikazu Sado, Yoshifumi Ninomiya, Dagmar Wilhelm, Raymond J. Rodgers. A New Model of Development of the Mammalian Ovary and Follicles. PLoS ONE, 2013; 8 (2): e55578 DOI: 10.1371/journal.pone.0055578

Cite This Page:

University of Adelaide. "Study prompts rethink of how ovaries develop." ScienceDaily. ScienceDaily, 11 February 2013. <www.sciencedaily.com/releases/2013/02/130211102059.htm>.
University of Adelaide. (2013, February 11). Study prompts rethink of how ovaries develop. ScienceDaily. Retrieved October 2, 2014 from www.sciencedaily.com/releases/2013/02/130211102059.htm
University of Adelaide. "Study prompts rethink of how ovaries develop." ScienceDaily. www.sciencedaily.com/releases/2013/02/130211102059.htm (accessed October 2, 2014).

Share This



More Health & Medicine News

Thursday, October 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Ebola Patient Told Hospital He Was from Liberia

Ebola Patient Told Hospital He Was from Liberia

AP (Oct. 1, 2014) The first Ebola patient diagnosed in the U.S. initially went to a Dallas emergency room last week but was sent home, despite telling a nurse that he had been in disease-ravaged West Africa, the hospital acknowledged Wednesday. (Oct. 1) Video provided by AP
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins