Featured Research

from universities, journals, and other organizations

Blood may hold clues to risk of memory problems after menopause

Date:
February 13, 2013
Source:
Mayo Clinic
Summary:
New research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood’s tendency to clot may contribute to areas of brain damage called white matter hyperintensities.

New Mayo Clinic research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities.

The findings are published in the Feb. 13 online issue of Neurology, the medical journal of the American Academy of Neurology.

The study involved 95 women with an average age of 53 who recently went through menopause. The women had magnetic resonance imaging, or MRIs, taken of their brains at the start of the study. They then received a placebo, oral hormone therapy or the hormone skin patch. They had MRIs periodically over the next four years.

During the study, women with higher levels of thrombogenic microvesicles, the platelets more likely to cause blood to clot, were likelier to have higher increases in the amount of white matter hyperintensities (shown as concentrated white areas on an MRI scan), which may lead to memory loss.

"This study suggests that the tendency of the blood to clot may contribute to a cascade of events leading to the development of brain damage in women who have recently gone through menopause," says study author Kejal Kantarci, M.D., of Mayo Clinic. "Preventing the platelets from developing these microvesicles could be a way to stop the progression of white matter hyperintensities in the brain."

All of the women had white matter hyperintensities at the start of the study. The amount increased by an average volume of 63 cubic millimeters at 18 months, 122 cubic millimeters at three years and 155 cubic millimeters at four years.

The study was supported by the National Institutes of Health (grants NS66147, HL90639, AG040042, RR024150, TR000135, HD65987 and AG044170), Aurora Foundation and Mayo Foundation.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Journal Reference:

  1. Limor Raz, M. Jayachandran, Nirubol Tosakulwong, Timothy G. Lesnick, Samantha M. Wille, Matthew C. Murphy, Matthew L. Senjem, Jeffrey L. Gunter, Prashanthi Vemuri, Clifford R. Jack, Jr, Virginia M. Miller, and Kejal Kantarci. Thrombogenic microvesicles and white matter hyperintensities in postmenopausal women. Neurology, 2013; DOI: 10.1212/WNL.0b013e3182840c9f

Cite This Page:

Mayo Clinic. "Blood may hold clues to risk of memory problems after menopause." ScienceDaily. ScienceDaily, 13 February 2013. <www.sciencedaily.com/releases/2013/02/130213165630.htm>.
Mayo Clinic. (2013, February 13). Blood may hold clues to risk of memory problems after menopause. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2013/02/130213165630.htm
Mayo Clinic. "Blood may hold clues to risk of memory problems after menopause." ScienceDaily. www.sciencedaily.com/releases/2013/02/130213165630.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins