Featured Research

from universities, journals, and other organizations

Insight on Pandemic Flu

Date:
April 25, 2013
Source:
Mississippi State University
Summary:
Pandemic flu continues to threaten public health, especially in the wake of the recent emergence of an H7N9 low pathogenic avian influenza strain in humans.

Pandemic flu continues to threaten public health, especially in the wake of the recent emergence of an H7N9 low pathogenic avian influenza strain in humans.

Related Articles


A recent study published in PLoS ONE, a peer-reviewed scientific journal, provides new information for public health officials on mitigating the spread of infection from emerging flu viruses. Dr. Henry Wan, associate professor at the Mississippi State University College of Veterinary Medicine led a study with researchers from Georgia Institute of Technology, Marshall University, and Universidad Miguel Hernández in Spain called "A perspective on multiple waves of influenza pandemics" that brings new insight into the H1N1 pandemic of 2009, and may help officials prepare for future pandemics.

During the 2009 H1N1 pandemic, along with the last three flu pandemics of 1918, 1957, and 1968, the United States experienced multiple peaks, or waves, of infection. Normal seasonal flu outbreaks have only one peak of infection--the number of cases starts very low, increases to a maximum, then decreases to a very low level, and remains at a low level until the next flu season. In this study, the team developed models to explain possible causes of the multiple peaks in pandemic flu, which are largely unknown.

"With the H1N1 pandemic in 2009, we experienced multiple waves of infection," Dr. Wan said. "The first wave began in March 2009 and peaked in late June and early July. Then there were fewer cases in August and then a second, larger wave hit in late October and early November. But China only experienced a single wave of infection. So we created infection models and analyzed the outcomes."

The models showed that border control had some small effects on outbreaks.

"In 2009, China instituted strict border controls at the onset of the outbreak," said first author Dr. Anna Mummert, assistant professor of mathematics at Marshall University. "We developed models explaining the occurrence of the multiple peaks and tested border control strategies to determine if a strict border control in the United States could reduce the total number of infections."

Four of the models indicated that if that stricter border control is related to fewer waves of infection.

"What was really remarkable was that all of the models showed that strong border control would not have decreased the total number of infections," said Dr. Howie Weiss, professor in Georgia Tech's School of Mathematics or College of Sciences.

The effects of vaccinations were studied in the models, and the authors concluded that the actual H1N1 vaccination distribution schedule played only a small role in curtailing the outbreak. While it has been thought that the timing of school vaccinations played a large role in producing the second wave of infections, the models did not show a strong link, but indicated that an earlier vaccination schedule could have helped.

The research team plans further collaboration in understanding influenza viruses and their spread.

"We are fortunate to have each other's expertise in mathematical modeling and infectious diseases," Wan said. "Our goal is to provide timely information to health organizations and others who work on infectious disease prevention."


Story Source:

The above story is based on materials provided by Mississippi State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mummert A, Weiss H, Long L-P, Amigó JM, Wan X-F. A Perspective on Multiple Waves of Influenza Pandemics. PLoS ONE, 8(4): e60343; 2013 DOI: 10.1371/journal.pone.0060343

Cite This Page:

Mississippi State University. "Insight on Pandemic Flu." ScienceDaily. ScienceDaily, 25 April 2013. <www.sciencedaily.com/releases/2013/04/130425091201.htm>.
Mississippi State University. (2013, April 25). Insight on Pandemic Flu. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2013/04/130425091201.htm
Mississippi State University. "Insight on Pandemic Flu." ScienceDaily. www.sciencedaily.com/releases/2013/04/130425091201.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins