Featured Research

from universities, journals, and other organizations

Flu shot effective regardless of circulating flu strain, research finds

Date:
June 25, 2013
Source:
St. Michael's Hospital
Summary:
New research has found that despite popular belief, the flu shot is effective in preventing the flu, even if the virus going around does not match the vaccine.

New research out of St. Michael's Hospital has found that despite popular belief, the flu shot is effective in preventing the flu, even if the virus going around does not match the vaccine.

"It's quite common for people to say they are not going to get the flu shot this year because they've heard it does not match the strain of flu going around," said Dr. Andrea Tricco, the lead author of the paper and a scientist at the Li Ka Shing Knowledge Institute of St. Michael's Hospital. "However, we've found that individuals will be protected regardless of whether the flu strain is a match or not."

The review of the literature analyzed more than 40 years of data, from 1971 to 2011, and included 47 influenza seasons and almost 95,000 healthy people.

Dr. Tricco and colleagues were particularly interested in flu seasons when the flu vaccines were not matched well to circulating strains. They wanted to understand whether the flu vaccines would still be effective when the strains were not a match.

Vaccines work by giving the body an inactive, or non-infective, form of the flu virus so that the body can produce antibodies. When an individual comes into contact with the virus in the future, the body can use the natural antibodies it has created to fight it off.

The study looked at the two most popular vaccine formulations in Canada -- Trivalent inactive vaccine for adults and live-attenuated influenza vaccine for children. They found that both vaccines provided significant protection against matched (ranging from 65 per cent to 83 per cent effectiveness) and mismatched (ranging from 52 per cent to 54 per cent effectiveness) flu strains.

The paper was published online in the journal BMC Medicine today.

"Looking at matches and mismatches can be a difficult process because it's not a yes or no variable," Dr. Tricco said. "Often we're looking at the degree of match between a flu strain and what's included in a vaccine because strains drift from year to year."

Dr. Tricco said that the study's results are mainly applicable to the seasonal flu in otherwise healthy children and adults.

The study was funded by GlaxoSmithKline.


Story Source:

The above story is based on materials provided by St. Michael's Hospital. The original article was written by Kate Taylor. Note: Materials may be edited for content and length.


Journal Reference:

  1. Andrea C Tricco, Ayman Chit, Charlene Soobiah, David Hallett, Genevieve Meier, Maggie H Chen, Mariam Tashkandi, Chris T Bauch, Mark Loeb. Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis. BMC Medicine, 2013; 11 (1): 153 DOI: 10.1186/1741-7015-11-153

Cite This Page:

St. Michael's Hospital. "Flu shot effective regardless of circulating flu strain, research finds." ScienceDaily. ScienceDaily, 25 June 2013. <www.sciencedaily.com/releases/2013/06/130625162235.htm>.
St. Michael's Hospital. (2013, June 25). Flu shot effective regardless of circulating flu strain, research finds. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2013/06/130625162235.htm
St. Michael's Hospital. "Flu shot effective regardless of circulating flu strain, research finds." ScienceDaily. www.sciencedaily.com/releases/2013/06/130625162235.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins