Featured Research

from universities, journals, and other organizations

Women's height linked to cancer risk, study finds

Date:
July 25, 2013
Source:
American Association for Cancer Research (AACR)
Summary:
The taller a postmenopausal woman is, the greater her risk for developing cancer, according to a new study.

New research finds that the taller a postmenopausal woman is, the greater her risk for developing cancer.
Credit: JPC-PROD / Fotolia

The taller a postmenopausal woman is, the greater her risk for developing cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Height was linked to cancers of the breast, colon, endometrium, kidney, ovary, rectum, and thyroid, as well as to multiple myeloma and melanoma, and these associations did not change even after adjusting for factors known to influence these cancers, in this study of 20,928 postmenopausal women, identified from a large cohort of 144,701 women recruited to the Women's Health Initiative (WHI).

"We were surprised at the number of cancer sites that were positively associated with height. In this data set, more cancers are associated with height than were associated with body mass index [BMI]," said Geoffrey Kabat, Ph.D., senior epidemiologist in the Department of Epidemiology and Population Health at Albert Einstein College of Medicine of Yeshiva University in New York, N.Y. "Ultimately, cancer is a result of processes having to do with growth, so it makes sense that hormones or other growth factors that influence height may also influence cancer risk."

Some genetic variations associated with height are also linked to cancer risk, and more studies are needed to better understand how these height-related genetic variations predispose some men and women to cancer, according to the authors.

Kabat and colleagues used data from the WHI, a large, multicenter study that recruited postmenopausal women between the ages 50 and 79, between 1993 and 1998. At study entry, the women answered questions about physical activity, and their height and weight were measured.

The researchers identified 20,928 women who had been diagnosed with one or more invasive cancers during the follow-up of 12 years. To study the effect of height, they accounted for many factors influencing cancers, including age, weight, education, smoking habits, alcohol consumption, and hormone therapy.

They found that for every 10-centimeter (3.94 inches) increase in height, there was a 13 percent increase in risk of developing any cancer. Among specific cancers, there was a 13 percent to 17 percent increase in the risk of getting melanoma and cancers of the breast, ovary, endometrium, and colon. There was a 23 percent to 29 percent increase in the risk of developing cancers of the kidney, rectum, thyroid, and blood.

Of the 19 cancers studied, none showed a negative association with height.

Because the ability to screen for certain cancers could have influenced the results, the researchers added the participants' mammography, Pap, and colorectal cancer screening histories to the analyses and found the results remained unchanged.

"Although it is not a modifiable risk factor [A modifiable risk factor can be changed, controlled, or treated, e.g., diet, lifestyle. Height is a non-modifiable risk factor because it cannot be changed], the association of height with a number of cancer sites suggests that exposures in early life, including nutrition, play a role in influencing a person's risk of cancer," said Kabat. "There is currently a great deal of interest in early-life events that influence health in adulthood. Our study fits with this area."


Story Source:

The above story is based on materials provided by American Association for Cancer Research (AACR). Note: Materials may be edited for content and length.


Journal Reference:

  1. Geoffrey C. Kabat, Matthew L. Anderson, Moonseong Heo, H. Dean Hosgood III, Victor Kamensky, Jennifer W. Bea, Lifang Hou, Dorothy S. Lane, Jean Wactawski-Wende, JoAnn E. Manson, and Thomas E. Rohan. Adult Stature and Risk of Cancer at Different Anatomic Sites in a Cohort of Postmenopausal Women. Cancer Epidemiol Biomarkers Prev, July 25, 2013 DOI: 10.1158/1055-9965.EPI-13-0305

Cite This Page:

American Association for Cancer Research (AACR). "Women's height linked to cancer risk, study finds." ScienceDaily. ScienceDaily, 25 July 2013. <www.sciencedaily.com/releases/2013/07/130725141521.htm>.
American Association for Cancer Research (AACR). (2013, July 25). Women's height linked to cancer risk, study finds. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2013/07/130725141521.htm
American Association for Cancer Research (AACR). "Women's height linked to cancer risk, study finds." ScienceDaily. www.sciencedaily.com/releases/2013/07/130725141521.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins