Featured Research

from universities, journals, and other organizations

New paradigm for nanoscale resolution MRI experimentally achieved

Date:
September 27, 2013
Source:
University of Illinois College of Engineering
Summary:
A team of researchers has devised a novel nuclear magnetic resonance imaging technique that delivers a roughly 10-nanometer spatial resolution. This represents a significant advance in MRI sensitivity -- modern MRI techniques commonly used in medical imaging yield spatial resolutions on the millimeter length scale, with the highest-resolution experimental instruments giving spatial resolution of a few micrometers.

Illustration of the experimental setup shows the two unique components of the teams novel MRI technique that was successful in producing a 2D MRI image with spatial resolution on the nanoscale.
Credit: University of Illinois

A team from the University of Illinois at Urbana-Champaign and Northwestern University has devised a novel nuclear magnetic resonance imaging (MRI) technique that delivers a roughly 10­nanometer spatial resolution. This represents a significant advance in MRI sensitivity -- modern MRI techniques commonly used in medical imaging yield spatial resolutions on the millimeter length scale, with the highest-resolution experimental instruments giving spatial resolution of a few micrometers.

"This is a very promising experimental result," said U. of I. physicist Raffi Budakian, who led the research effort. "Our approach brings MRI one step closer in its eventual progress toward atomic-scale imaging."

MRI is used widely in clinical practice to distinguish pathologic tissue from normal tissue. It is noninvasive and harmless to the patient, using strong magnetic fields and non-ionizing electromagnetic fields in the radio frequency range, unlike CT scans and tradiational X-rays, which both use more harmful ionizing radiation.

MRI uses static and time-dependent magnetic fields to detect the collective response of large ensembles of nuclear spins from molecules localized within millimeter-scale volumes in the body. Increasing the detection resolution from the millimeter to nanometer range would be a technological dream come true.

The team's breakthrough -- the new technique introduces two unique components to overcome obstacles to applying classic pulsed magnetic resonance techniques in nanoscale systems. First, a novel protocol for spin manipulation applies periodic radio-frequency magnetic field pulses to encode temporal correlations in the statistical polarization of nuclear spins in the sample. Second, a nanoscale metal constriction focuses current, generating intense magnetic field-pulses.

In their proof-of-principal demonstration, the team used an ultrasensitive magnetic resonance sensor based on a silicon nanowire oscillator to reconstruct a two-dimensional projection image of the proton density in a polystyrene sample at nanoscale spatial resolution.

"We expect this new technique to become a paradigm for nanoscale magnetic-resonance imaging and spectroscopy into the future," added Budakian. "It is compatible with and can be incorporated into existing conventional MRI technologies."


Story Source:

The above story is based on materials provided by University of Illinois College of Engineering. Note: Materials may be edited for content and length.


Journal Reference:

  1. John M. Nichol, Tyler R. Naibert, Eric R. Hemesath, Lincoln J. Lauhon, Raffi Budakian. Nanoscale Fourier-Transform Magnetic Resonance Imaging. Physical Review X, 2013; 3 (3) DOI: 10.1103/PhysRevX.3.031016

Cite This Page:

University of Illinois College of Engineering. "New paradigm for nanoscale resolution MRI experimentally achieved." ScienceDaily. ScienceDaily, 27 September 2013. <www.sciencedaily.com/releases/2013/09/130927123504.htm>.
University of Illinois College of Engineering. (2013, September 27). New paradigm for nanoscale resolution MRI experimentally achieved. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2013/09/130927123504.htm
University of Illinois College of Engineering. "New paradigm for nanoscale resolution MRI experimentally achieved." ScienceDaily. www.sciencedaily.com/releases/2013/09/130927123504.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) — After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) — A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) — Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) — Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins