Featured Research

from universities, journals, and other organizations

Low thyroid levels may signal heightened risk of death in hospitalized patients

Date:
October 30, 2013
Source:
Endocrine Society
Summary:
Older individuals hospitalized with a serious condition may face a slimmer risk of surviving if their thyroid hormone levels are low, according to a recent study.

Older individuals hospitalized with a serious condition may face a slimmer risk of surviving if their thyroid hormone levels are low, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

The thyroid gland, located in the neck, produces hormones that regulate the body's temperature, consumption of oxygen, and metabolism. The gland produces two hormones, triiodothyronine (T3) and thyroxine (T4), which travel through the blood to spur activity in various tissues.

"When older individuals have low levels of thyroid hormones, particularly T3, it reflects that the body is weak and more susceptible to the harmful effects of disease," said the study's first author Pedro Iglesias, MD, of Hospital Ramón y Cajal in Madrid, Spain. "As a result, older individuals who have a reduced ability to synthesize T3 hormones have a higher rate of mortality, both in the short- and long-term."

As part of the prospective observational study, researchers measured thyroid hormone levels in all patients who were 65 years of age or older when they were admitted to the Hospital General in Segovia, Spain in 2005. For 404 patients, researchers tracked the length of hospital stay and the survival rate among the group as of Jan. 1, 2012.

During the seven-year study, 323 patients died. The study found an association between low levels of thyroid hormones and mortality. The analysis found low levels of thyroid hormone, in particular T3, tended to be a predictor for all-cause mortality. The patients in the group with the lowest levels of T3 hormones and thyroid-stimulating hormone, which the body uses to activate the thyroid gland, also had higher rates of death from cardiovascular disease.

"T3 could be a useful measure for gauging an older individual's chances of surviving an acute illness requiring hospitalization," Iglesias said. "The reduced ability to synthesize the hormone observed in this group of patients could be related to the severity of the disease and its prognosis."

Other researchers working on the study include: E. Ridruejo, A. Muñoz, F. Prado, M. Macías, M. Guerrero, P. Tajada and C. García-Arévalo of Hospital General in Segovia, Spain, and J.J. Díez of Hospital Ramón y Cajal in Madrid, Spain.

The article, "Thyroid Function Tests and Mortality in Aged Hospitalized Patients: a 7-year Prospective Observational Study," is scheduled to appear in the December 2013 issue of JCEM.


Story Source:

The above story is based on materials provided by Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. P. Iglesias, E. Ridruejo, A. Munoz, F. Prado, M. C. Macias, M. T. Guerrero, P. Tajada, C. Garcia-Arevalo, J. J. Diez. Thyroid Function Tests and Mortality in Aged Hospitalized Patients: A 7-Year Prospective Observational Study. Journal of Clinical Endocrinology & Metabolism, 2013; DOI: 10.1210/jc.2012-3849

Cite This Page:

Endocrine Society. "Low thyroid levels may signal heightened risk of death in hospitalized patients." ScienceDaily. ScienceDaily, 30 October 2013. <www.sciencedaily.com/releases/2013/10/131030132711.htm>.
Endocrine Society. (2013, October 30). Low thyroid levels may signal heightened risk of death in hospitalized patients. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2013/10/131030132711.htm
Endocrine Society. "Low thyroid levels may signal heightened risk of death in hospitalized patients." ScienceDaily. www.sciencedaily.com/releases/2013/10/131030132711.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) — The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) — An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) — Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) — Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins