Featured Research

from universities, journals, and other organizations

Liver transplant survival rates lower in black than white pediatric patients

Date:
December 5, 2013
Source:
Wiley
Summary:
Novel research reveals racial and socioeconomic disparities among pediatric liver transplant patients. Findings indicate that graft and patient survival was higher in white children than minorities. Studies show that over the last 30 years pediatric patient survival, at one year following liver transplant, is 90% compared to 70% prior to 1980. Experts suggest that as survival rates improve, understanding racial and socioeconomic differences in pediatric populations are important factors to consider.

Novel research reveals racial and socioeconomic disparities among pediatric liver transplant patients. Findings published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, indicate that graft and patient survival was higher in white children than minorities.

Related Articles


For patients with end-stage liver disease (ESLD) the only treatment option for survival is liver transplantation. Studies show that over the last 30 years pediatric patient survival, at one year following liver transplant, is 90% compared to 70% prior to 1980. Experts suggest that as survival rates improve, understanding racial and socioeconomic differences in pediatric populations are important factors to consider for overall health status.

"Little is known about the impact of race, ethnicity and socioeconomic status disparities on outcomes after liver transplantation among pediatric and adolescent recipients," explains first author Rekha Thammana, MD of Emory University Department of Medicine in Atlanta, GA. "Our study is the first to investigation the impact of race and socioeconomic status on graft and patient survival among white and minority children."

Researchers included 208 liver transplant recipients, aged 22 or younger, who were transplanted at Children's Hospital of Atlanta between January 1998 and December 2008. Participants were followed through November 2011. Data from the United Network for Organ Sharing (UNOS) on transplant outcomes and donor characteristics was linked with Georgia Transplant Foundation financial aid data to examine the contribution of socioeconomic status to the observed racial disparities.

Results show that 51% of transplant recipients were white, 35% were black and 14% were other races or ethnicities. At 1, 3, 5, and 10 years following liver transplant the graft and patient survival was higher among white children compared to the minority children. The 10-year graft survival was 84% for white, 60% among black and 49% for the remaining minority patients. Patient survival at 10 years post-transplant was 92%, 65%, and 76% among whites, blacks, and other races, respectively.

Further analyses show that graft failure and mortality rates remained higher among minority groups compared to white children after accounting for differences in demographic, clinical, and socioeconomic factors. "While our study determined differences in post-transplant outcomes between minority and white pediatric liver transplant recipients, we were unable to fully explain the reason for these disparities," concluded senior author Rachel Patzer, PhD, MPH with the Division of Transplantation at Emory University. "Further investigation of the reasons for racial and ethnic differences, particularly on a national level, is necessary to identify interventions that may help reduce disparities in pediatric liver transplantation."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. R.V. Thammana , S. J. Knechtle, R. Romero, T. G. Heffron, C. T. Daniels and R. E. Patzer. Racial and Socioeconomic Disparities in Pediatric and Young Adult Liver Transplant Outcomes. Liver Transplantation, December 2013

Cite This Page:

Wiley. "Liver transplant survival rates lower in black than white pediatric patients." ScienceDaily. ScienceDaily, 5 December 2013. <www.sciencedaily.com/releases/2013/12/131205141547.htm>.
Wiley. (2013, December 5). Liver transplant survival rates lower in black than white pediatric patients. ScienceDaily. Retrieved December 23, 2014 from www.sciencedaily.com/releases/2013/12/131205141547.htm
Wiley. "Liver transplant survival rates lower in black than white pediatric patients." ScienceDaily. www.sciencedaily.com/releases/2013/12/131205141547.htm (accessed December 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, December 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Americans Drink More in the Winter

Americans Drink More in the Winter

Buzz60 (Dec. 22, 2014) The BACtrack breathalyzer app analyzed Americans' blood alcohol content and found out a whole lot of interesting things about their drinking habits. Mara Montalbano (@maramontalbano) has more. Video provided by Buzz60
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins