Featured Research

from universities, journals, and other organizations

Exercise can reduce drug-related joint pain in breast cancer patients, study shows

Date:
December 12, 2013
Source:
Dana-Farber Cancer Institute
Summary:
Women being treated with breast cancer drugs known as aromatase inhibitors can markedly ease the joint pain associated with the drugs by engaging in moderate daily exercise, investigators report in a study.

Women being treated with breast cancer drugs known as aromatase inhibitors can markedly ease the joint pain associated with the drugs by engaging in moderate daily exercise, Dana-Farber Cancer Institute and Yale University investigators report in a study to be presented during the San Antonio Breast Cancer Symposium.

The study involved 121 postmenopausal women who were taking aromatase inhibitors for breast cancer and who rated their joint pain as mild or greater on a standard pain-evaluation questionnaire. Sixty-one of them were randomly assigned to participate in two supervised strength training sessions a week and to engage in an average of 150 minutes of aerobic exercise a week. The others followed their normal daily activities.

After a year, joint pain scores decreased by 20 percent among the women in the exercise group and by three percent in the other group. The severity of joint pain also decreased significantly more in those who exercised than in those who didn't, as did the degree to which pain interfered with their lives.

"This is one of the first studies to identify an approach -- particularly a non-medical approach -- that can effectively lower joint pain for these patients," says the study's senior author, Jennifer Ligibel, MD, of the Susan F. Smith Center for Women's Cancers at Dana-Farber. "Exercise offers an attractive option for patients who want to continue taking these drugs but who are burdened by their side effects."

Aromatase inhibitors are recommended for all postmenopausal women with breast cancer categorized as hormone receptor-positive, meaning the cancer cells grow and divide in response to estrogen. The drugs, which prevent other hormones from being converted into estrogen, can reduce the risk of a cancer recurrence.

"Joint pain, or arthralgia, which occurs in up to half of breast cancer patients who take aromatase inhibitors, is one of the major drawbacks of these drugs," Ligibel states. "The pain leads many to discontinue the drugs, which can increase the chance that the cancer will return. Identifying a way to help women tolerate these drugs is a very important finding."


Story Source:

The above story is based on materials provided by Dana-Farber Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Dana-Farber Cancer Institute. "Exercise can reduce drug-related joint pain in breast cancer patients, study shows." ScienceDaily. ScienceDaily, 12 December 2013. <www.sciencedaily.com/releases/2013/12/131212094928.htm>.
Dana-Farber Cancer Institute. (2013, December 12). Exercise can reduce drug-related joint pain in breast cancer patients, study shows. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2013/12/131212094928.htm
Dana-Farber Cancer Institute. "Exercise can reduce drug-related joint pain in breast cancer patients, study shows." ScienceDaily. www.sciencedaily.com/releases/2013/12/131212094928.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins