Featured Research

from universities, journals, and other organizations

Study to determine if vitamin D supplements will improve mood in women with type 2 diabetes

Date:
February 24, 2014
Source:
Loyola University Health System
Summary:
Researchers are recruiting women for a study to determine whether raising blood levels of vitamin D can improve mood in women with diabetes. The study also will examine whether raising vitamin D levels can reduce blood pressure and affect how well women manage their diabetes. The study will explore whether vitamin D supplementation decreases inflammation, thus providing evidence for a plausible mechanism for how the vitamin works as an antidepressant. About 1 in 10 people in the United States has diabetes, and the incidence is projected to increase to 1 in 4 persons by 2050. Women with type 2 diabetes have worse outcomes than men. The reason may be due to depression, which affects more than 25 percent of women with diabetes. Depression impairs a patient's ability to manage her disease.

Loyola University Chicago Marcella Niehoff School of Nursing researchers are recruiting women for a study to determine whether raising blood levels of vitamin D can improve mood in women with diabetes. The study also will examine whether raising vitamin D levels can reduce blood pressure and affect how well women manage their diabetes.

Related Articles


Principal investigator Sue M. Penckofer, PhD, RN, and colleagues hypothesize that women who have low levels of vitamin D and receive weekly doses of 50,000 IUs of vitamin D3 will report a better mood than those who receive weekly doses of 5,000 IUs.

"Using a higher dose of vitamin D is potentially an easy and cost-effective way to improve mood," Dr. Penckofer said. "Improving mood may make these women more likely to eat properly, take their medication, get enough exercise and better manage their disease overall."

Penckofer and her Loyola co-investigators received a $1.49 million grant (R01NR013906) for the study from the National Institute of Nursing Research at the National Institutes of Health. Women who are eligible are between the ages of 21 and 75 and have type 2 diabetes, low levels of vitamin D in their blood, are overweight and report symptoms of depression. Women will be randomly assigned to receive one of the two doses for six months. The study began enrolling women in November 2013 and will continue until 2017.

Earlier studies have found that depressed people have elevated levels of inflammatory biomarkers, notably cytokines and C-reactive protein (CRP). The study will explore whether vitamin D supplementation decreases inflammation, thus providing evidence for a plausible mechanism for how the vitamin works as an antidepressant.

About 1 in 10 people in the United States has diabetes, and the incidence is projected to increase to 1 in 4 persons by 2050. Women with type 2 diabetes have worse outcomes than men. The reason may be due to depression, which affects more than 25 percent of women with diabetes. Depression impairs a patient's ability to manage her disease.

Many Americans do not get enough vitamin D, and people with diabetes are prone to vitamin D insufficiency or deficiency. The exact mechanisms behind this are not known, but may include limited intake of foods high in vitamin D, obesity, lack of sun exposure, and genetic variations.

Penckofer is internationally known for her research on vitamin D, diabetes, and depression. Her co-investigators are Angelos Halaris, MD, PhD; Ramon Durazo, PhD; Pauline Camacho, MD, Joanne Kouba, PhD, RD, Mary Ann Emanuele, MD, and Patricia Mumby, PhD.

For more information, call 708.216.9303.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Cite This Page:

Loyola University Health System. "Study to determine if vitamin D supplements will improve mood in women with type 2 diabetes." ScienceDaily. ScienceDaily, 24 February 2014. <www.sciencedaily.com/releases/2014/02/140224171255.htm>.
Loyola University Health System. (2014, February 24). Study to determine if vitamin D supplements will improve mood in women with type 2 diabetes. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2014/02/140224171255.htm
Loyola University Health System. "Study to determine if vitamin D supplements will improve mood in women with type 2 diabetes." ScienceDaily. www.sciencedaily.com/releases/2014/02/140224171255.htm (accessed October 26, 2014).

Share This



More Health & Medicine News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
Toxin-Packed Stem Cells Used To Kill Cancer

Toxin-Packed Stem Cells Used To Kill Cancer

Newsy (Oct. 25, 2014) — A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins