Featured Research

from universities, journals, and other organizations

Transplantation cell therapy offers hope to stroke patients

Date:
April 7, 2014
Source:
American Association of Neurological Surgeons (AANS)
Summary:
Researchers who conducted intraparenchymal transplantation of bone marrow-derived cell therapy in chronic stroke patients are poised to present their results of a recent study. The clinical findings have led to new studies using brain stimulation of circuits to restore neurologic function in animal stroke models.

The devastating effects of stroke have long led physicians to conclude that lost brain function is irreversible. During the 82nd Annual Scientific Meeting of the American Association of Neurological Surgeons (AANS), researchers presented the results of a groundbreaking study that offers new hope to stroke patients.

Related Articles


In the first North American trial of its kind, researchers conducted intraparenchymal transplantation of bone marrow-derived cell therapy in chronic stroke patients. Titled A Novel Phase 1/2A Study of Intraparenchymal Transplantation of Human Modified Bone Marrow Derived Cells in Patients with Stable Ischemic Stroke, the study tested the feasibility of administering escalated doses of stromal cells. Numerous preclinical animal stroke studies showing the benefit of stem cell transplantation led to the initiation of this clinical trial.

The study was led by Gary K. Steinberg, MD, PhD, FAANS: "Although this was primarily a safety study, we found a significant recovery of neurologic function in patients overall at six months that is sustained at one year. Two of the 18 transplanted patients showed remarkable improvement."

Transplanted patients continued to recover substantial neurologic function two years or more following their stroke, said Dr. Steinberg: "This suggests that the affected neural circuits following stroke are not dead, but potentially still viable and can be reactivated, which is contrary to the currently accepted dogma."

The clinical findings have led to new studies using brain stimulation of circuits to restore neurologic function in animal stroke models.


Story Source:

The above story is based on materials provided by American Association of Neurological Surgeons (AANS). Note: Materials may be edited for content and length.


Cite This Page:

American Association of Neurological Surgeons (AANS). "Transplantation cell therapy offers hope to stroke patients." ScienceDaily. ScienceDaily, 7 April 2014. <www.sciencedaily.com/releases/2014/04/140407153808.htm>.
American Association of Neurological Surgeons (AANS). (2014, April 7). Transplantation cell therapy offers hope to stroke patients. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2014/04/140407153808.htm
American Association of Neurological Surgeons (AANS). "Transplantation cell therapy offers hope to stroke patients." ScienceDaily. www.sciencedaily.com/releases/2014/04/140407153808.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins