Featured Research

from universities, journals, and other organizations

Oncologists aim to fast-track personalized cancer therapy

Date:
June 25, 2014
Source:
KU Leuven
Summary:
Cancer is incredibly complex, and each tumor is unique. This calls for a targeted approach. Researchers want to fight cancer by developing ‘personalized’ cancer therapies. "Despite the progress made in fighting cancer in recent years, we are all too often powerless. That is the reality. But it should not deter us," they say.

Cancer is incredibly complex, and each tumor is unique. This calls for a targeted approach. Researchers at KU Leuven's Department of Oncology, in Belgium, want to fight cancer by developing 'personalised' cancer therapies. To bolster their efforts, they have established the new Fund for Innovative Cancer Research.

Professor Frιdιric Amant is chair of the fund: "Despite the progress made in fighting cancer in recent years, we are all too often powerless. That is the reality. But it should not deter us. Our goal in establishing this fund is to finance projects that transcend the domains of oncology and have the potential to produce real breakthroughs."

The fund is now seeking financial support for the tumor Xenograft Project, its first major fundraising target. The project is dedicated to a promising line of cancer research that significantly narrows the gap between success in the lab and success in the patient.

The 'Patient-Derived tumor Xenograft Model' is a technique for gaining more and better information about a tumor. Professor Frιdιric Amant: "The tumor Xenograft Model is a patient-specific approach. By implanting cancerous tissue samples from the patient into mice, we can study the tumor and gain insight into its structure and development, just as if it were growing in the patient."

The researchers comb through the tumor's genetic and other characteristics looking for 'biomarkers' that can be targeted by both experimental and proven therapies.

These therapies are then tested on mice carrying the tumor. If a therapy shows promising results in the mice, there is a good chance it will also be effective in the patient.

Treatments found to work for one patient can also be used to provide targeted care for other patients with tumors exhibiting the same biomarker.

The researchers want to use the promising 'tumor Xenograft Model' to study as many tumor types as possible. Insights gained can be used to develop personalised therapies that give each patient the best possible chance of beating their tumor while also minimising side effects.

Because some cancer types are extremely rare, international cooperation is essential. Tissue samples gathered during the project will be included in an international bio-bank and made available to oncologists around the world.

There are no new therapies without innovative research. In establishing this fund, the Leuven researchers call on the support and involvement of the pharmaceutical and technology industries, government and members of the public.


Story Source:

The above story is based on materials provided by KU Leuven. Note: Materials may be edited for content and length.


Cite This Page:

KU Leuven. "Oncologists aim to fast-track personalized cancer therapy." ScienceDaily. ScienceDaily, 25 June 2014. <www.sciencedaily.com/releases/2014/06/140625114719.htm>.
KU Leuven. (2014, June 25). Oncologists aim to fast-track personalized cancer therapy. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2014/06/140625114719.htm
KU Leuven. "Oncologists aim to fast-track personalized cancer therapy." ScienceDaily. www.sciencedaily.com/releases/2014/06/140625114719.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) — Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) — Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) — Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) — Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins