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June 1, 2021 Researchers have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and ...
Feb. 16, 2022 Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and ...
Aug. 30, 2023 A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were ...
Apr. 9, 2021 For those who have sickle cell disease, there are only a few treatment options, which include bone marrow transplants, gene therapy or other treatments that address a subset of symptoms. Now, ...
Dec. 13, 2021 An experimental gene therapy for sickle cell disease restored blood cells to their normal shape and eliminated severe pain crises for years after treatment, a multicenter study has ...
Jan. 29, 2024 Researchers have revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their findings enhance strong evidence of hydroxyurea's effectiveness and could ...
May 6, 2021 Scientists have developed a highly efficient method to address a major challenge in biology -- identifying the genetic 'switches' that regulate gene ...
Oct. 12, 2022 Scientists found the cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for some common genetic ...
Nov. 16, 2023 Researchers have discovered that 'cell competition' following gene therapy results in the accumulation of stem cells with genetic mutations which make them grow faster. Some of these ...
July 1, 2021 New research finds that certain factors, such as a history of severe pain episodes and coexisting organ conditions, increase the risk of severe COVID-19 illness, including hospitalization, in ...