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Sickle-cell disease

Sickle cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S).

In many forms of the disease, the red blood cells change shape upon deoxygenation because of polymerization of the abnormal sickle hemoglobin.

Note:   The above text is excerpted from the Wikipedia article "Sickle-cell disease", which has been released under the GNU Free Documentation License.
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August 31, 2015

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