Featured Research

from universities, journals, and other organizations

Hyperactivity Linked To Thyroid Hormones

Date:
March 12, 1997
Source:
University of Maryland at Baltimore
Summary:
Thyroid hormone may play a role in the hyperactive and impulsive symptoms of children with attention deficit-hyperactivity disorder.

For information, interviews contact: Jennifer Donovanphone: (410) 706-7946; pager: (410) 407-6873email: JenniferD@oia-2.ab.umd.edu

Related Articles


HYPERACTIVITY LINKED TO THYROID HORMONESThyroid hormone may play a role in the hyperactive and impulsive symptoms of children with attention deficit-hyperactivity disorder (ADHD), University of Maryland School of Medicine researchers say. Dr. Peter Hauser, professor of psychiatry, and Dr. Bruce Weintraub, professor of medicine at the University of Maryland School of Medicine, have found a positive correlation between elevated levels of certain thyroid hormones and hyperactivity/impulsivity in a selected group of patients. They report on their research in the February issue of the international journal Psychoneuroendocrinology.

ADHD is one of the most common psychiatric problems of childhood, affecting an estimated three to five out of every 100 children. But up to now, no studies have demonstrated a physiologic basis for the differences between those suffering merely from inattention and those displaying symptoms of hyperactivity and impulsive behavior, a trait psychiatrists call impulsivity.

Having previously discovered a strong and specific association between resistance to thyroid hormone and ADHD, Hauser, Weintraub and colleagues studied 75 people diagnosed with resistance to thyroid hormone and 77 of their unaffected family members. They measured levels of three thyroid hormones - TSH, T3 and T4 - and evaluated symptoms of both inattention and hyperactivity, two constellations of symptoms that together make up ADHD.

Resistance to thyroid hormone is a thyroid disease characterized by elevated levels of serum T3 and T4, as well as inappropriately normal or high concentrations of serum TSH, evidence of a reduced response to the actions of thyroid hormones. ADHD symptoms were identified in interviews by psychologists and psychiatrists who did not know which subjects had resistance to thyroid hormone.

TSH concentrations did not correlate significantly with any of the symptoms of ADHD. High concentrations of T3 and T4, while not significant in symptoms of inattention, were significantly and positively correlated with symptoms of hyperactivity/impulsivity in thyroid hormone-resistant subjects, Hauser said.

In family members who were not resistant to thyroid hormone, neither TSH nor T4 concentrations were significantly correlated with ADHD. Elevated levels of T3, however, were signicantly correlated with hyperactivity/impulsivity symptoms but not with symptoms of inattention, he reported.

"The correlation between thyroid hormone concentrations and symptoms of hyperactivity does not prove causality," warned Hauser, chief of psychiatry at the Baltimore Veterans Affairs Medical Center, a University of Maryland School of Medicine teaching hospital. "What it does show is that thyroid hormones may provide a physiologic basis for the dichotomy between symptoms of inattention and symptoms of hyperactivity."

Hauser said the study supports the American Pyschiatric Association’s decision to combine the symptoms of hyperactivity and impulsivity in their 1994 revision of the Diagnostic Manual of Mental Disorders, the bible of psychiatric diagnosis in the United States.

"Our findings suggest that further research on the role of thyroid hormone in subjects with ADHD may be of benefit," he said.

Research data were collected while Hauser and Weintraub were on the staff of the Molecular and Cellular Endocrinology Branch of the National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, which funded the research.END


Story Source:

The above story is based on materials provided by University of Maryland at Baltimore. Note: Materials may be edited for content and length.


Cite This Page:

University of Maryland at Baltimore. "Hyperactivity Linked To Thyroid Hormones." ScienceDaily. ScienceDaily, 12 March 1997. <www.sciencedaily.com/releases/1997/03/970312165726.htm>.
University of Maryland at Baltimore. (1997, March 12). Hyperactivity Linked To Thyroid Hormones. ScienceDaily. Retrieved January 31, 2015 from www.sciencedaily.com/releases/1997/03/970312165726.htm
University of Maryland at Baltimore. "Hyperactivity Linked To Thyroid Hormones." ScienceDaily. www.sciencedaily.com/releases/1997/03/970312165726.htm (accessed January 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, January 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins