December 25, 1997
Washington University In St. Louis
Investigators at Washington University School of Medicine in St. Louis have identified the first factor to significantly boost human leptin concentrations. And surprisingly, this substance also boosted leptin levels in some overweight individuals.
Leptin leapt into the headlines when it was identified in 1995 as a protein that triggers weight loss in mice. But the appetite-taming hormone lost some luster as the ultimate diet drug when scientists found last year that obese people already have high levels of leptin in their blood. This finding suggested that overweight people may become unable to respond to leptin, though little is known about leptin's interactions in the body.
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Washington University In St. Louis. "Regulator Of Fat Thermostat Found." ScienceDaily. ScienceDaily, 25 December 1997. <www.sciencedaily.com/releases/1997/12/971225183203.htm>.
Washington University In St. Louis. (1997, December 25). Regulator Of Fat Thermostat Found. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/1997/12/971225183203.htm
Washington University In St. Louis. "Regulator Of Fat Thermostat Found." ScienceDaily. www.sciencedaily.com/releases/1997/12/971225183203.htm (accessed April 19, 2014).