Featured Research

from universities, journals, and other organizations

Natural Substances Shows Promise In Cancer Prevention, Treatment

Date:
June 8, 1998
Source:
University Of Maryland, Baltimore
Summary:
Animal studies using human cancer cells show that a natural sugar-phospate compound found in rice and wheat bran and legumes slows or stops the growth of several kinds of cancer and shrinks existing tumors.

Animal studies using human cancer cells show that a natural sugar-phosphate compound normally found in rice and wheat bran and in legumes slows or stops the growth of several kinds of cancer and shrinks existing tumors, a University of Maryland pathologist told an international scientific symposium today (June 8). The First International Symposium on Disease Prevention by IP6 and Other Rice Components is being held in Kyoto, Japan on June 8-9.

Related Articles


Abulkalam M. Shamsuddin, MD, PhD, a University of Maryland School of Medicine professor of pathology who helped organize the symposium, reported on his research on the cancer-fighting properties of inositol hexaphosphate (IP6) in colon, liver, breast and soft-tissue cancers in human cell-lines transplanted into mice.

"The number of tumors and their size was reduced three-fold," Shamsuddin said. "The rate of cell division was cut in half. IP6 also normalizes cell division and up-regulates the product of the P53 gene, one of the body’s most powerful tumor-suppressor genes."

In the May-June issue of the journal Anticancer Research, Shamsuddin and colleagues at the University of Maryland and the National Cancer Institute report on studies in which IP6 effectively inhibited cell growth and shrank existing tumors almost 50-fold. Treated cells also began to differentiate again, a sign of a return to normal.

In a presentation which concluded the two-day symposium, Shamsuddin summarized 14 years of his own research and that of about a dozen other scientists worldwide. In addition to effectiveness in prevention and treatment of a variety of kinds of tumors, IP6 has been shown to inhibit kidney stone formation, lower lipid levels in the blood, prevent fatty liver, protect the muscles in the heart wall during heart attack and prevent atherosclerosis, he said.

IP6 is a sugar molecule attached to six phosphate molecules. It is found throughout nature, in plants and virtually every kind of mammalian cell. It plays in important role in regulating cell proliferation and differentiation.

"IP6 has striking anticancer action, both in vitro (in a test tube) and in vivo (in live animals)," says Shamsuddin. He is hoping to conduct human clinical trials soon.


Story Source:

The above story is based on materials provided by University Of Maryland, Baltimore. Note: Materials may be edited for content and length.


Cite This Page:

University Of Maryland, Baltimore. "Natural Substances Shows Promise In Cancer Prevention, Treatment." ScienceDaily. ScienceDaily, 8 June 1998. <www.sciencedaily.com/releases/1998/06/980608053930.htm>.
University Of Maryland, Baltimore. (1998, June 8). Natural Substances Shows Promise In Cancer Prevention, Treatment. ScienceDaily. Retrieved April 21, 2015 from www.sciencedaily.com/releases/1998/06/980608053930.htm
University Of Maryland, Baltimore. "Natural Substances Shows Promise In Cancer Prevention, Treatment." ScienceDaily. www.sciencedaily.com/releases/1998/06/980608053930.htm (accessed April 21, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, April 21, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Blue Bell Recalls All Products

Blue Bell Recalls All Products

AP (Apr. 21, 2015) Blue Bell Creameries voluntary recalled for all of its products after two samples of chocolate chip cookie dough ice cream tested positive for listeria, a potentially deadly bacteria. Blue Bell&apos;s President and CEO issued a video statement. (April 21) Video provided by AP
Powered by NewsLook.com
'Tutu Tuesdays' Brighten Faces at Kids' Hospital

'Tutu Tuesdays' Brighten Faces at Kids' Hospital

AP (Apr. 21, 2015) Doctors and nurses have started wearing ballet tutus every Tuesday to cheer up young hospital patients at a Florida hospital. It started with a request made by a nervous patient -- now, almost the entire staff is wearing the tutus. (April 21) Video provided by AP
Powered by NewsLook.com
Humanoid Robot Can Recognise and Interact With People

Humanoid Robot Can Recognise and Interact With People

Reuters - Innovations Video Online (Apr. 20, 2015) An ultra-realistic humanoid robot called &apos;Han&apos; recognises and interprets people&apos;s facial expressions and can even hold simple conversations. Developers Hanson Robotics hope androids like Han could have uses in hospitality and health care industries where face-to-face communication is vital. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Labour Party Warns Britain's Health Service 'on Life Support'

Labour Party Warns Britain's Health Service 'on Life Support'

AFP (Apr. 20, 2015) Britain&apos;s opposition Labour Party Monday claimed the National Health Service (NHS) was &apos;on life support&apos; as it turned its attention to the state-run service, which is a key issue for the UK&apos;s May 7 general election. Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins