Featured Research

from universities, journals, and other organizations

Natural Substances Shows Promise In Cancer Prevention, Treatment

Date:
June 8, 1998
Source:
University Of Maryland, Baltimore
Summary:
Animal studies using human cancer cells show that a natural sugar-phospate compound found in rice and wheat bran and legumes slows or stops the growth of several kinds of cancer and shrinks existing tumors.

Animal studies using human cancer cells show that a natural sugar-phosphate compound normally found in rice and wheat bran and in legumes slows or stops the growth of several kinds of cancer and shrinks existing tumors, a University of Maryland pathologist told an international scientific symposium today (June 8). The First International Symposium on Disease Prevention by IP6 and Other Rice Components is being held in Kyoto, Japan on June 8-9.

Abulkalam M. Shamsuddin, MD, PhD, a University of Maryland School of Medicine professor of pathology who helped organize the symposium, reported on his research on the cancer-fighting properties of inositol hexaphosphate (IP6) in colon, liver, breast and soft-tissue cancers in human cell-lines transplanted into mice.

"The number of tumors and their size was reduced three-fold," Shamsuddin said. "The rate of cell division was cut in half. IP6 also normalizes cell division and up-regulates the product of the P53 gene, one of the body’s most powerful tumor-suppressor genes."

In the May-June issue of the journal Anticancer Research, Shamsuddin and colleagues at the University of Maryland and the National Cancer Institute report on studies in which IP6 effectively inhibited cell growth and shrank existing tumors almost 50-fold. Treated cells also began to differentiate again, a sign of a return to normal.

In a presentation which concluded the two-day symposium, Shamsuddin summarized 14 years of his own research and that of about a dozen other scientists worldwide. In addition to effectiveness in prevention and treatment of a variety of kinds of tumors, IP6 has been shown to inhibit kidney stone formation, lower lipid levels in the blood, prevent fatty liver, protect the muscles in the heart wall during heart attack and prevent atherosclerosis, he said.

IP6 is a sugar molecule attached to six phosphate molecules. It is found throughout nature, in plants and virtually every kind of mammalian cell. It plays in important role in regulating cell proliferation and differentiation.

"IP6 has striking anticancer action, both in vitro (in a test tube) and in vivo (in live animals)," says Shamsuddin. He is hoping to conduct human clinical trials soon.


Story Source:

The above story is based on materials provided by University Of Maryland, Baltimore. Note: Materials may be edited for content and length.


Cite This Page:

University Of Maryland, Baltimore. "Natural Substances Shows Promise In Cancer Prevention, Treatment." ScienceDaily. ScienceDaily, 8 June 1998. <www.sciencedaily.com/releases/1998/06/980608053930.htm>.
University Of Maryland, Baltimore. (1998, June 8). Natural Substances Shows Promise In Cancer Prevention, Treatment. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/1998/06/980608053930.htm
University Of Maryland, Baltimore. "Natural Substances Shows Promise In Cancer Prevention, Treatment." ScienceDaily. www.sciencedaily.com/releases/1998/06/980608053930.htm (accessed September 1, 2014).

Share This




More Health & Medicine News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins