A research team based at the Massachusetts General Hospital (MGH) has found that inactivation of a single gene in female mice can sustain ovarian function into advanced age. The report in the February issue of Nature Genetics describes how female mice in which a gene called Bax is inactivated do not experience the normal loss of ovarian cells that occurs throughout the animal' lifetime.
The above story is based on materials provided by Massachusetts General Hospital. Note: Materials may be edited for content and length.
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Massachusetts General Hospital. "Gene Knockout Prolongs Ovarian Lifespan In Mice." ScienceDaily. ScienceDaily, 2 February 1999. <www.sciencedaily.com/releases/1999/02/990202072624.htm>.
Massachusetts General Hospital. (1999, February 2). Gene Knockout Prolongs Ovarian Lifespan In Mice. ScienceDaily. Retrieved March 7, 2014 from www.sciencedaily.com/releases/1999/02/990202072624.htm
Massachusetts General Hospital. "Gene Knockout Prolongs Ovarian Lifespan In Mice." ScienceDaily. www.sciencedaily.com/releases/1999/02/990202072624.htm (accessed March 7, 2014).