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Research Links Healthy Biological Clock To Longevity

Date:
March 29, 1999
Source:
University Of Toronto
Summary:
Aging hamsters who received a new biological clock had their lifespan increased by 20 per cent, proving the importance of circadian rhythms to the health and longevity of an organism.

Aging hamsters who received a new biological clock had their lifespan increased by 20 per cent, proving the importance of circadian rhythms to the health and longevity of an organism.

Once the biological clock of a hamster begins to deteriorate, death occurs within three months. However, when University of Toronto psychologist Martin Ralph transplanted a new clock into hamsters whose own clocks had begun to deteriorate, they lived an average of four months longer than hamsters without the transplant -- roughly a 20 per cent increase in their lifespan.

A biological clock is a small piece of brain tissue that generates a rhythm controlling the day/night behaviour of an organism. When this rhythm breaks down, as it does in many aging humans, it leads to numerous health problems including disrupted sleep patterns and poor body temperature control. Ralph says that while it is highly unlikely humans will ever receive new biological clocks, behaviour modification might achieve similar results.

"If the function of the clock can be mimicked by a structured lifestyle, such as more light during the day and darkness at night, then this will work in the same direction as the transplant works in hamsters," he says.

Ralph collaborated with Mark Hurd of the University of Houston. The study was supported by the National Institute on Aging in the United States and the Natural Sciences and Engineering Research Council in Canada.

CONTACT:
Kerry Delaney
U of T Public Affairs
(416) 978-5948
kerry.delaney@utoronto.ca


Story Source:

The above story is based on materials provided by University Of Toronto. Note: Materials may be edited for content and length.


Cite This Page:

University Of Toronto. "Research Links Healthy Biological Clock To Longevity ." ScienceDaily. ScienceDaily, 29 March 1999. <www.sciencedaily.com/releases/1999/03/990325111049.htm>.
University Of Toronto. (1999, March 29). Research Links Healthy Biological Clock To Longevity . ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/1999/03/990325111049.htm
University Of Toronto. "Research Links Healthy Biological Clock To Longevity ." ScienceDaily. www.sciencedaily.com/releases/1999/03/990325111049.htm (accessed August 30, 2014).

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