Featured Research

from universities, journals, and other organizations

UT Southwestern Study To Test Efficacy Of St. John's Wort For Treatment Of Depression

Date:
May 4, 1999
Source:
University Of Texas Southwestern Medical Center At Dallas
Summary:
Dr. Madhukar Trivedi, associate professor of psychiatry at UT Southwestern Medical Center at Dallas, is seeking volunteers for the first controlled U.S. study of this popular plant derivative, known scientifically as hypericum, for the treatment of major depression.

Dallas -- Twenty-eight-year-old artist Leslie Kenegar has a group of her paintings that she hides in her back closet and describes as "just for me - I don't want anybody else to know I've felt that way." On her other walls, however, hang the bright paintings she's done in her sunny moods.

Related Articles


What makes the difference? Kenegar thinks the answer lies with St. John's wort, said Dr. Madhukar Trivedi, associate professor of psychiatry at UT Southwestern Medical Center at Dallas. He is seeking volunteers for the first controlled U.S. study of this popular plant derivative, known scientifically as hypericum, for the treatment of major depression.

Trivedi, who is a specialist in researching and treating depression, said he doesn't know whether St. John's wort is effectively treating Kenegar and the depression of others or not - and that's just the point.

"The more we know about depression and its treatments the better," he said. "Many people believe that this supplement, easily obtained in health-food stores and neighborhood pharmacies, is helpful in improving their sad, low moods. But it has not been studied in this country, and the European studies were not conducted with the same tight controls as our research at UT Southwestern."

Although there are now several classes of drugs that work well for patients who suffer from depression, Trivedi said that all medications don't work for all people. "The more medications we develop, the more people we will be able to help," he said. "And patients should understand that they still need to be monitored by a physician when taking St. John's wort for depression."

St. John's wort, which has been used for mood elevation over many centuries, has grown in popularity recently, along with ginseng and other products considered natural.

Participants in the three-month study must be 18 years of age or older. Each will be given the St. John's wort drug; sertraline, a serotonin re-uptake inhibitor; or a placebo (sugar pill).

Kenegar won't be able to participate in the study because she's already taking the medication. But she said she'd be waiting to learn the outcome because she agrees with Trivedi that scientists need to learn more about natural substances that people are taking for medicinal purposes.

The National Institute of Mental Health agreed to fund the project without financial input from pharmaceutical companies.

###

For information on the St. John's wort study, call 214-648-8333.


Story Source:

The above story is based on materials provided by University Of Texas Southwestern Medical Center At Dallas. Note: Materials may be edited for content and length.


Cite This Page:

University Of Texas Southwestern Medical Center At Dallas. "UT Southwestern Study To Test Efficacy Of St. John's Wort For Treatment Of Depression." ScienceDaily. ScienceDaily, 4 May 1999. <www.sciencedaily.com/releases/1999/05/990504070350.htm>.
University Of Texas Southwestern Medical Center At Dallas. (1999, May 4). UT Southwestern Study To Test Efficacy Of St. John's Wort For Treatment Of Depression. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/1999/05/990504070350.htm
University Of Texas Southwestern Medical Center At Dallas. "UT Southwestern Study To Test Efficacy Of St. John's Wort For Treatment Of Depression." ScienceDaily. www.sciencedaily.com/releases/1999/05/990504070350.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins