Featured Research

from universities, journals, and other organizations

Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents

Date:
May 10, 1999
Source:
University Of Illinois At Urbana-Champaign
Summary:
Instead of traveling to Brazil's tropical rain forest or diving into the ocean, a team of University of Illinois scientists are looking for disease-fighting compounds closer to home, harvesting potential agents from the trash piles of byproducts at crop-processing plants.

CHAMPAIGN, Ill. -- Instead of traveling to Brazil's tropical rain forest or diving into the ocean, a team of University of Illinois scientists are looking for disease-fighting compounds closer to home, harvesting potential agents from the trash piles of byproducts at crop-processing plants.

Initial laboratory tests on cultured mammalian and human cells indicate an ethanol extract of soybean molasses represses the ability of at least one dietary carcinogen to damage the DNA of normal cells, the researchers report. Details will appear in the journal "Teratogenesis, Carcinogenesis and Mutagenesis." At the Environmental Mutagen Society Meeting, March 27 to April 1, in Washington, D.C., the team announced that the structure of the active compound -- named phytochemical complex 100 (PCC 100) -- contains a combination of chemicals known as saponins. Very little work has been done on their biological effects.

The team also reported at the meeting that PCC suppresses the growth rate of cancer cells and that an isolated soy-protein fraction drastically reduces the growth rate of human colon cancer. The work was based on a newly developed cell-growth kinetic assay.

The soy protein finding did not come as a surprise, because the apparent positive effects of soy protein and its estrogen-like isoflavones have been documented. But the still-evolving technique may allow scientists to more precisely identify the specific protein agents and the anti-cancer mechanisms that are involved, said team leader Michael J. Plewa, a geneticist in the department of crop sciences.

"It is strange to be running off to the rain forest to yank up weird plants when we may already be sitting on mountains of very useful pharmaceutical agents in our own corn and soybean fields," he said. "During crop processing, raw materials are modified by mechanical disruption, chemical extraction and changes in temperatures and pressures. Agents you take out of plants for food or processing products may not necessarily be the ones that are actually in the plants or seeds themselves. They may have been modified."

Plewa's team includes U. of I. colleagues A. Lane Rayburn, B.A. Francis and several students, and M. Berhow of the U.S. Department of Agriculture. Collaborative work is continuing with BIBRA International in the United Kingdom and Archer Daniels Midland Co. in Decatur, Ill. Funding for exploring the byproducts and developing assays to find anti-mutagens and anti-carcinogens comes from the U.S. Soybean Board and Illinois Soybean Operating Board.

"We are looking to prevent environmental carcinogens ingested in our diet from affecting normal cells in our bodies, and to isolate agents that slow down the growth rate of already existing cancer cells," Plewa said. "If we can repress their growth, we might be able to extend the use and heighten the effectiveness of therapeutic drugs, chemotherapy and radiation."


Story Source:

The above story is based on materials provided by University Of Illinois At Urbana-Champaign. Note: Materials may be edited for content and length.


Cite This Page:

University Of Illinois At Urbana-Champaign. "Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents." ScienceDaily. ScienceDaily, 10 May 1999. <www.sciencedaily.com/releases/1999/05/990510064003.htm>.
University Of Illinois At Urbana-Champaign. (1999, May 10). Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/1999/05/990510064003.htm
University Of Illinois At Urbana-Champaign. "Trash From Crop-Processing Plant Harvested For Disease-Fighting Agents." ScienceDaily. www.sciencedaily.com/releases/1999/05/990510064003.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins